diff --git a/MdeModulePkg/Bus/Pci/XhciDxe/Xhci.c b/MdeModulePkg/Bus/Pci/XhciDxe/Xhci.c
index 7f64f9c7c982..636ed875297b 100644
--- a/MdeModulePkg/Bus/Pci/XhciDxe/Xhci.c
+++ b/MdeModulePkg/Bus/Pci/XhciDxe/Xhci.c
@@ -803,7 +803,10 @@ XhcTransfer (
   *TransferResult = Urb->Result;
   *DataLength     = Urb->Completed;
 
-  if ((*TransferResult == EFI_USB_ERR_STALL) || (*TransferResult == EFI_USB_ERR_BABBLE)) {
+  //
+  // Based on XHCI spec 4.8.3, software should do the reset endpoint while USB Transaction occur.
+  //
+  if ((*TransferResult == EFI_USB_ERR_STALL) || (*TransferResult == EFI_USB_ERR_BABBLE) || (*TransferResult == EDKII_USB_ERR_TRANSACTION)) {
     ASSERT (Status == EFI_DEVICE_ERROR);
     RecoveryStatus = XhcRecoverHaltedEndpoint(Xhc, Urb);
     if (EFI_ERROR (RecoveryStatus)) {
diff --git a/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.c b/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.c
index 75959ae08363..b006501551d9 100644
--- a/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.c
+++ b/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.c
@@ -1174,8 +1174,11 @@ XhcCheckUrbResult (
         DEBUG ((EFI_D_ERROR, "XhcCheckUrbResult: ERR_BUFFER! Completecode = %x\n",EvtTrb->Completecode));
         goto EXIT;
 
+      //
+      // Based on XHCI spec 4.8.3, software should do the reset endpoint while USB Transaction occur.
+      //
       case TRB_COMPLETION_USB_TRANSACTION_ERROR:
-        CheckedUrb->Result  |= EFI_USB_ERR_TIMEOUT;
+        CheckedUrb->Result  |= EDKII_USB_ERR_TRANSACTION;
         CheckedUrb->Finished = TRUE;
         DEBUG ((EFI_D_ERROR, "XhcCheckUrbResult: TRANSACTION_ERROR! Completecode = %x\n",EvtTrb->Completecode));
         goto EXIT;
diff --git a/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.h b/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.h
index b5e192c3b589..d180c1aa2e9a 100644
--- a/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.h
+++ b/MdeModulePkg/Bus/Pci/XhciDxe/XhciSched.h
@@ -83,6 +83,13 @@ WITHOUT WARRANTIES OR REPRESENTATIONS OF ANY KIND, EITHER EXPRESS OR IMPLIED.
 #define TRB_COMPLETION_STOPPED                26
 #define TRB_COMPLETION_STOPPED_LENGTH_INVALID 27
 
+//
+// USB Transfer Results Internal Definition
+// Based on XHCI spec 4.8.3, software should do the reset endpoint while USB Transaction occur.
+// Add the error code for USB Transaction error since UEFI spec don't have the related definition.
+//
+#define EDKII_USB_ERR_TRANSACTION  0x200
+
 //
 // The topology string used to present usb device location
 //