diff --git a/bottleneck/include/iterators.h b/bottleneck/include/iterators.h
index 1f5120a18..8be840f77 100644
--- a/bottleneck/include/iterators.h
+++ b/bottleneck/include/iterators.h
@@ -87,9 +87,6 @@ static inline void init_iter_all(iter *it, PyArrayObject *a, int ravel, int anyo
     it->nits = 1;
     it->a_ravel = NULL;
 
-    /* The fix for relaxed strides checking in numpy and the fix for
-   * issue #183 has left this if..else tree in need of a refactor from the
-   * the ground up */
     if (ndim == 1) {
         it->ndim_m2 = -1;
         it->length = shape[0];
@@ -98,47 +95,12 @@ static inline void init_iter_all(iter *it, PyArrayObject *a, int ravel, int anyo
         it->ndim_m2 = -1;
         it->length = 1;
         it->astride = 0;
-    } else if (C_CONTIGUOUS(a) && !F_CONTIGUOUS(a)) {
-        /* The &&! in the next two else ifs is to deal with relaxed
-     * stride checking introduced in numpy 1.12.0; see gh #161 */
+    } else if (C_CONTIGUOUS(a) || (anyorder && F_CONTIGUOUS(a))) {
+        /* If continguous then we just need the itemsize */
         it->ndim_m2 = -1;
-        it->axis = ndim - 1;
+        // it->axis does not matter
         it->length = PyArray_SIZE(a);
-        it->astride = 0;
-        for (i = ndim - 1; i > -1; i--) {
-            /* protect against length zero  strides such as in
-       * np.ones((2, 2))[..., np.newaxis] */
-            if (strides[i] == 0) {
-                continue;
-            }
-            it->astride = strides[i];
-            break;
-        }
-    } else if (F_CONTIGUOUS(a) && !C_CONTIGUOUS(a)) {
-        if (anyorder || !ravel) {
-            it->ndim_m2 = -1;
-            it->length = PyArray_SIZE(a);
-            it->astride = 0;
-            for (i = 0; i < ndim; i++) {
-                /* protect against length zero  strides such as in
-         * np.ones((2, 2), order='F')[np.newaxis, ...] */
-                if (strides[i] == 0) {
-                    continue;
-                }
-                it->astride = strides[i];
-                break;
-            }
-        } else {
-            it->ndim_m2 = -1;
-            if (anyorder) {
-                a = (PyArrayObject *)PyArray_Ravel(a, NPY_ANYORDER);
-            } else {
-                a = (PyArrayObject *)PyArray_Ravel(a, NPY_CORDER);
-            }
-            it->a_ravel = a;
-            it->length = PyArray_DIM(a, 0);
-            it->astride = PyArray_STRIDE(a, 0);
-        }
+        it->astride = item_size;
     } else if (ravel) {
         it->ndim_m2 = -1;
         if (anyorder) {
diff --git a/bottleneck/tests/reduce_test.py b/bottleneck/tests/reduce_test.py
index 56723e1d9..02298dd1b 100644
--- a/bottleneck/tests/reduce_test.py
+++ b/bottleneck/tests/reduce_test.py
@@ -236,3 +236,31 @@ def test_ddof_nans(func, dtype):
     for axis in [None, 0, 1, -1]:
         result = func(array, axis=axis, ddof=3)
         assert np.isnan(result)
+
+
+@pytest.mark.parametrize("dtype", DTYPES)
+@pytest.mark.parametrize(
+    ("func", "expected"),
+    [(bn.nansum, 1000),
+     (bn.nanmean, 1),
+     (bn.nanmax, 1)],
+    ids=lambda x: x.__name__ if not isinstance(x, int) else x
+)
+def test_reduce_with_unordered_strides_ccontig(func, expected, dtype) -> None:
+    array = np.ones((1, 500, 2), dtype=dtype).transpose((1,2,0))
+    result = func(array)
+    assert result == expected
+
+@pytest.mark.parametrize("dtype", DTYPES)
+@pytest.mark.parametrize(
+    ("func", "expected"),
+    [(bn.nansum, 1000),
+     (bn.nanmean, 1),
+     (bn.nanmax, 1)],
+    ids=lambda x: x.__name__ if not isinstance(x, int) else x
+)
+def test_reduce_with_unordered_strides_fcontig(func, expected, dtype) -> None:
+    array = np.ones((1, 500, 2), dtype=dtype).transpose((0,2,1))
+    result = func(array)
+    assert result == expected
+