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LensCorrect

Tools for calibrating and applying lens correction models to multi-channel and split-image microscopy data from light and electron microscopy. This is useful to calculate lens-distortion models for distortion free stitching and/ or chromatic abberation.

There are four CLI sub commands:

Usage: lens-correct [-hV] [COMMAND]
Calculate and apply lens-distortion corrections from and to multi-channel and
split-image microscopy stacks.
  -h, --help      Show this help message and exit.
  -V, --version   Print version information and exit.
Commands:
  help                Display help information about the specified command.
  calibrate-split     Calibrate lens distortion and align split-images or lens
                        arrays
  apply-split         Apply lens-distortion correction and alignment to stacks
                        of split-images or lens arrays
  apply-channels      Apply wavelength-dependent lens-distortion correction and
                        alignment to multi-channel image stacks
  calibrate-channels  Calibrate lens distortion and align multi-channel image
                        stacks

Split calibration

Documented here.

Multi-channel calibration

Explained here, follow the split instructions.

Installation

Use the released installation package for your OS or build it yourself.

References

This method is an extension of the method developed for lens-distortion and chromatic aberration correction by Bogovic et al. (2020). PLOS ONE 15(12): e0236495 which is an extension of the method developed for lens-distortion corrections and alignment across uncalibrated TEM systems by Zheng et al. (2018). Cell 174(3):730-743.e22 which is an extension of the method developed for lens-distortion correction of TEM images by Kaynig et al. (2010). J Struct Biol. 171(2):163-73 and implemented in TrakEM2 by Cardona et al. (2012). PLoS ONE 7(6), e38011.