We are a research group at Heidelberg University and the European Bioinformatics Institute, part of the European Molecular Biology Laboratory (EMBL-EBI).
Our goal is to acquire a functional understanding of the deregulation of signalling networks in disease and to apply this knowledge to develop novel therapeutics. We focus on cancer, heart failure, auto-immune and fibrotic disease. Towards this goal, we integrate big (‘omics’) data with mechanistic molecular knowledge into statistical and machine learning methods. To this end, we have developed a range of tools in different areas of biomedical research, mainly using the programming languages R and Python.
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