diff --git a/pyproject.toml b/pyproject.toml
index e479e266c..fb23a2a6e 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -101,7 +101,7 @@ test-min = [
     "pyarrow<21",        # https://github.com/scikit-hep/awkward/issues/3579
     "anndata[dask]",
 ]
-test = [ "anndata[test-min,lazy]" ]
+test = [ "anndata[test-min,lazy]", "jax", "jaxlib" ] # TODO: remove jax? own extra?
 gpu = [ "cupy" ]
 cu12 = [ "cupy-cuda12x" ]
 cu11 = [ "cupy-cuda11x" ]
diff --git a/src/anndata/_core/index.py b/src/anndata/_core/index.py
index 5ed271add..a9177f78f 100644
--- a/src/anndata/_core/index.py
+++ b/src/anndata/_core/index.py
@@ -10,7 +10,7 @@
 import pandas as pd
 from scipy.sparse import issparse
 
-from ..compat import AwkArray, CSArray, CSMatrix, DaskArray, XDataArray
+from ..compat import AwkArray, CSArray, CSMatrix, DaskArray, XDataArray, has_xp
 from .xarray import Dataset2D
 
 if TYPE_CHECKING:
@@ -115,8 +115,11 @@ def name_idx(i):
         if isinstance(indexer.data, DaskArray):
             return indexer.data.compute()
         return indexer.data
+    elif has_xp(indexer):
+        msg = "Need to implement array api-based indexing"
+        raise NotImplementedError(msg)
     msg = f"Unknown indexer {indexer!r} of type {type(indexer)}"
-    raise IndexError()
+    raise IndexError(msg)
 
 
 def _fix_slice_bounds(s: slice, length: int) -> slice:
diff --git a/src/anndata/_core/storage.py b/src/anndata/_core/storage.py
index e3e00ba7d..42afc50b8 100644
--- a/src/anndata/_core/storage.py
+++ b/src/anndata/_core/storage.py
@@ -10,7 +10,7 @@
 from anndata.compat import CSArray, CSMatrix
 
 from .._warnings import ImplicitModificationWarning
-from ..compat import XDataset
+from ..compat import XDataset, has_xp
 from ..utils import (
     ensure_df_homogeneous,
     join_english,
@@ -67,6 +67,8 @@ def coerce_array(
             return np.array(value)
         except (ValueError, TypeError) as _e:
             e = _e
+    if has_xp(value):
+        return value
     # if value isn’t the right type or convertible, raise an error
     msg = f"{name} needs to be of one of {join_english(map(str, array_data_structure_types))}, not {type(value)}."
     if e is not None:
diff --git a/src/anndata/_core/views.py b/src/anndata/_core/views.py
index ac9a0dd0f..a7f74ef27 100644
--- a/src/anndata/_core/views.py
+++ b/src/anndata/_core/views.py
@@ -21,6 +21,7 @@
     CupyCSRMatrix,
     DaskArray,
     ZappyArray,
+    has_xp,
 )
 from .access import ElementRef
 from .xarray import Dataset2D
@@ -292,6 +293,9 @@ def __setattr__(self, key: str, value: Any):
 
 @singledispatch
 def as_view(obj, view_args):
+    if has_xp(obj):
+        # TODO: Determine if we need some sort of specific view object for array-api
+        return obj
     msg = f"No view type has been registered for {type(obj)}"
     raise NotImplementedError(msg)
 
diff --git a/src/anndata/compat/__init__.py b/src/anndata/compat/__init__.py
index 6eb4da48b..c49ca2a62 100644
--- a/src/anndata/compat/__init__.py
+++ b/src/anndata/compat/__init__.py
@@ -12,6 +12,7 @@
 import numpy as np
 import pandas as pd
 import scipy
+from array_api_compat import get_namespace as array_api_get_namespace
 from packaging.version import Version
 from zarr import Array as ZarrArray  # noqa: F401
 from zarr import Group as ZarrGroup
@@ -415,3 +416,11 @@ def _map_cat_to_str(cat: pd.Categorical) -> pd.Categorical:
         return cat.map(str, na_action="ignore")
     else:
         return cat.map(str)
+
+
+def has_xp(mod):
+    try:
+        array_api_get_namespace(mod)
+        return True
+    except TypeError:
+        return False
diff --git a/tests/test_obsmvarm.py b/tests/test_obsmvarm.py
index e2513e3a8..02bf136df 100644
--- a/tests/test_obsmvarm.py
+++ b/tests/test_obsmvarm.py
@@ -144,6 +144,13 @@ def test_setting_daskarray(adata: AnnData):
     assert h == joblib.hash(adata)
 
 
+def test_setting_jax(adata: AnnData):
+    import jax.numpy as jnp
+
+    adata.obsm["jax"] = jnp.ones((adata.shape[0], 10))
+    assert isinstance(adata.obsm["jax"], jnp.ndarray)
+
+
 def test_shape_error(adata: AnnData):
     with pytest.raises(
         ValueError,
diff --git a/tests/test_views.py b/tests/test_views.py
index 29a02b503..4e12f251b 100644
--- a/tests/test_views.py
+++ b/tests/test_views.py
@@ -824,6 +824,48 @@ def test_index_float_sequence_raises_error(index):
         gen_adata((10, 10))[index]
 
 
+def test_jax_indexer():
+    import jax.numpy as jnp
+
+    index = np.array([0, 3, 6])
+    index_jax = jnp.array(index)
+    adata = gen_adata((10, 10))
+    assert_equal(adata[index], adata[index_jax])
+
+
+@pytest.mark.parametrize(
+    "index",
+    [
+        np.array([0, 3, 6]),
+        slice(3),
+        Ellipsis,
+        (np.array([0, 3, 6]), np.array([1, 4, 7])),
+        (
+            np.array([([True] * 5) + ([False] * 5)]),
+            np.array([([True] * 5) + ([False] * 5)]),
+        ),
+        (
+            np.array([0, 3, 6]),
+            np.array([([True] * 5) + ([False] * 5)]),
+        ),
+    ],
+    ids=[
+        "integer-array",
+        "slice",
+        "ellipsis",
+        "two-axis-integer-arrays",
+        "two-axis-boolean-arrays",
+        "mixed-array-type",
+    ],
+)
+def test_index_into_jax(index):
+    import jax.numpy as jnp
+
+    adata = ad.AnnData(X=np.ones((10, 10)))
+    adata_as_jax = ad.AnnData(X=jnp.ones((10, 10)))
+    assert_equal(adata[index], adata_as_jax[index])
+
+
 # @pytest.mark.parametrize("dim", ["obs", "var"])
 # @pytest.mark.parametrize(
 #     ("idx", "pat"),
diff --git a/tests/test_x.py b/tests/test_x.py
index d7da59a0c..c1ebfe840 100644
--- a/tests/test_x.py
+++ b/tests/test_x.py
@@ -192,3 +192,9 @@ def test_fail_on_non_csr_csc_matrix():
         match=r"Only CSR and CSC.*",
     ):
         ad.AnnData(X=X)
+
+
+def test_create_anndata_with_jax():
+    import jax.numpy as jnp
+
+    ad.AnnData(X=jnp.ones((10, 10)))