scVI used to have a within cluster DE test that I used often, but I no longer see this functionality in scvi-tools. Is it possible to add it back?
This would be a differential expression function where a "groupby" argument would specify a set of groups (e.g., cell clusters) and a "states" argument would specify the relevant comparison to make (e.g., case vs control). The output would include the DE test results from a comparison of cases vs controls within each specified group.
scVI used to have a within cluster DE test that I used often, but I no longer see this functionality in scvi-tools. Is it possible to add it back?
This would be a differential expression function where a "groupby" argument would specify a set of groups (e.g., cell clusters) and a "states" argument would specify the relevant comparison to make (e.g., case vs control). The output would include the DE test results from a comparison of cases vs controls within each specified group.