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Description
- Spearman
- other methods from dist
- straight function
GenomicSuperSignature/R/validate.R
Lines 15 to 37 in 5e73d06
| .loadingCor <- function(dataset, avgLoading, method = "pearson", scale = FALSE) { | |
| if (any(class(dataset) == "ExpressionSet")) { | |
| dat <- Biobase::exprs(dataset) | |
| } else if (any(class(dataset) %in% c("SummarizedExperiment", "RangedSummarizedExperiment"))) { | |
| dat <- SummarizedExperiment::assay(dataset) | |
| } else if (any(class(dataset) == "matrix")) { | |
| dat <- dataset | |
| } else { | |
| stop("'dataset' should be one of the following objects: ExpressionSet, | |
| SummarizedExperiment, RangedSummarizedExperiment, and matrix.") | |
| } | |
| if (isTRUE(scale)) {dat <- rowNorm(dat)} # row normalization | |
| dat <- dat[apply(dat, 1, function (x) {!any(is.na(x) | (x==Inf) | (x==-Inf))}),] | |
| gene_common <- intersect(rownames(avgLoading), rownames(dat)) | |
| prcomRes <- stats::prcomp(t(dat[gene_common,])) # centered, but not scaled by default | |
| loadings <- prcomRes$rotation[, 1:8] | |
| loading_cor <- abs(stats::cor(avgLoading[gene_common,], loadings[gene_common,], | |
| use = "pairwise.complete.obs", | |
| method = method)) | |
| return(loading_cor) | |
| } |
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