v0.6.6

• Fixed bug in exported oncopharmadb data.frame
• Updated biomarkers

v0.6.5

• NCI Thesaurus 2021.12d
• Added preliminary set of drug biomarkers, data frames that can be acccessed directly through
  • oncoPharmaDB::compound_biomarkers$curated - curated evidence linking genomic aberrations to drug response - harvested from CIViC, CGI, and PMKB
  • oncoPharmaDB::compound_biomarkers$invitro_screen - from DepMap/PRISM, indicating predictive omics features of drug response in cancer cell lines

v0.6.3

• NCI Thesaurus update (v21.11e)

v0.6.2 - OTP 2021.11

• code/documentation improvements after devtools::check()
• data from Open Targets Platform

v0.6.1

• Data update: NCI Thesaurus (21.10d)
• Removed some redundant/non-informative columns of main data frame (oncopharmadb)
  • target_chembl_id
  • drug_synonyms
  • drug_description
  • drug_moa
  • drug_tradenames
  • cancer_drug
• Documented exported data objects (oncopharmadb and oncopharma_synonyms)
• Annotated gonadotropin releasing hormone analogues with hormone_therapy label
• Added platinum_compound as a dedicated drug category (and as a column in oncopharmadb)
  • New argument is_platinum_compound to get_onco_drugs()

v0.6.0 - OTP 2021.09

• Retrieved latest drug collection (release 2021.09) from Open Targets Platform (ChEMBL++)

v0.5.4 - NCI update

• Fixed ambiguous assignment of drug categories
• Updated NCI thesaurus to 21.09d

Initial release

• Initial release of oncoPharmaDB - R package to retrieve antineoplastic drugs
• Users can query across targets, indications, action types etc.
• Users can furthermore return resulting drug records at different "resolutions" (i.e. drug2target, drug2target2indication etc)