.NET Framework 4.6.2 fully implements .NET Standard 2.0 and there is no code using anything specific to .NET Framework 4.6.2. So, .NET Standard 2.0 is enough to cover that.
.NET Core 3.1, .NET 5.0 and .NET 6.0 fully implements .NET Standard 2.1 and there is no code using anything specific to .NET Core 3.1, .NET 5.0 or .NET 6.0. So, .NET Standard 2.1 is enough to cover that.
There might be some usage of .NET 6.0 features in the future, but I would delay targeting it specifically to when that happens.
.NET Standard