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Things to check:
How pseudoinputs move accross epochs:
Things that may help integration:
- Different proportions of 2 systems (e.g. if we have prior components only from one system this may force other to be closer)
- Do prior components of the two systems migrate closer to each other during training?
Notes on analysis:
- Would use only cell types that are well represented in both species
- Balancing of N components per ct may be useful so that in all 3 settings (priors from both systems or one of the two systems) have same number of components per ct.
Notes on VAMP:
- Takes as pseudoinputs real data (expression, covar) and embeds them to get prior components.
- The pseudoinputs change during training, leading to their embed (prior components) also changing,
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