Why not remove usb2uart and usb hub?

[hallym6cn]

Why not remove usb2uart and usb hub?
We can flash it by usb

[aytekinasarardi-ui]

When I connect the card to the computer, it doesn't show up in Device Manager. I tried different cables, but it still didn't work; the ESP32 and RP2040 ports aren't responding. Have you ever encountered a problem like this?