🧬 GeneChain

GeneChain is a bioinformatics project that helps users explore detailed information about specific genes, including:

• 🔍 Gene details (e.g., function, pathways)
• 💊 Medicines associated with the gene
• 🦠 Diseases linked to the gene
• 🧪 Other genes related to or interacting with the input gene

This tool is useful for researchers, healthcare developers, and anyone interested in genomics and precision medicine.

🚀 Features

• Search a gene using its ID (e.g., from KEGG)
• Fetch associated diseases and syndromes
• Get recommended or related drugs
• Display similar or related genes from the same pathway or network
• Store and reuse pathway objects for faster querying

🧠 Tech Stack

• Frontend: HTML, CSS, JavaScript
• Backend: Python, Flask
• Database: SQLite3
• Data Source: KEGG REST API
• Libraries: requests, json, and bioinformatics utilities

🛠 Usage

• **Start the application: python app.py
• **Open your web browser and navigate to:http://localhost:5000

🌐 KEGG API Examples

Here are some useful KEGG API endpoints used by the application:

• 🔗 Pathway Details (hsa00982)
• 🔗 Link a Gene to Pathways (TP53 - hsa:7157)
• 🔗 Get Gene Info (BRCA1 - hsa:672)