Pipeline for: Restoring endogenous Dlg4/PSD95 expression by an artificial transcription factor ameliorates cognitive and motor learning deficits in the R6/2 mouse model of Huntington’s disease

https://doi.org/10.1186/s13148-025-01903-2

Installing Dependencies

All R package dependencies are listed in Install.R. To install them run either of the following commands from the project root:

# using Rscript
./install_packages.sh

or within an R session:

source("Install.R")

The project uses R r-2022-01-01 (see runtime.txt). For reproducible package versions you may create an renv.lock file with:

install.packages("renv")
renv::snapshot()

A helper script install_missing.R is provided to install only packages that are not already present.