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Copy file name to clipboardExpand all lines: README.md
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New Cellpose4 models added! We have included new Cellpose models based on [DINOv3](https://github.com/facebookresearch/dinov3), `cpdino` and `cpdino-vitb`.
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We have also updated the CellposeSAM model (`cpsam_v2`), and it now predicts fewer spurious masks in low-contrast regions.
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To use the new models, `pip install cellpose[dino] --upgrade`, and find more details [here](https://cellpose.readthedocs.io/en/latest/models.html).
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To use the new models, `pip install cellpose --upgrade` and `pip install git+https://github.com/facebookresearch/dinov3`, and find more details [here](https://cellpose.readthedocs.io/en/latest/models.html).
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:triangular_flag_on_post: All Cellpose models are trained on data that is licensed under **CC-BY-NC**. The Cellpose annotated dataset is also CC-BY-NC.
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3. Create a new environment with `conda create --name cellpose python=3.12`. We recommend python 3.12, but python 3.9 and 3.11 will also work.
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4. To activate this new environment, run `conda activate cellpose`
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5. (option 1) To install cellpose with the GUI, run `python -m pip install cellpose[gui]`. If you're on a zsh server, you may need to use ' ': `python -m pip install 'cellpose[gui]'`.
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6. (option 2) To install cellpose without the GUI, run `python -m pip install cellpose[dino]`.
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6. (option 2) To install cellpose without the GUI, run `python -m pip install cellpose`.
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7. Install the DINOv3 package to use the CellposeDINO models with `python -m pip install git+https://github.com/facebookresearch/dinov3`.
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To upgrade cellpose (package [here](https://pypi.org/project/cellpose/)), run the following in the environment:
Copy file name to clipboardExpand all lines: docs/models.rst
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We have four built-in models available:
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* ``cpdino``: this is the CellposeDINO model released in June 2026 using the DINOv3-ViTL backbone
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* ``cpsam_v2``: this is the CellposeSAM model released in June 2026 using the SAM-ViTL backbone, it includes a fix in the training for low contrast regions
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* ``cpdino``: this is the CellposeDINO model released in June 2026 using the DINOv3-ViTL backbone
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* ``cpdino-vitb``: this is the CellposeDINO model released in June 2026 using the DINOv3-ViTB backbone (smaller model)
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* ``cpsam``: this is the original CellposeSAM model released in April 2025 using the SAM-ViTL backbone
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