Electrophysiological Cancer Cell Model

Attempt to model an A549 cancer cell's ion channels using an HMM (Hidden Markov Model) and simulation of voltage + current development accross the membrane of the cell.

This software comes in three flavours:

• to run the main.rs simulation, do cargo run,
• to compile the Python module, do maturin develop --features pyo3,
• to precompile for the Astro dashboard, do bun run wasm-pack build frontend.

A visual to capture your interest:

(Image source: here).

This computational model is based on Langthaler et al., 2021: A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma.

The Simulation Dashboard