The Surrounding Chemical Space

This section is for any other molecules out there that are similar to Series 3.

TCAMS Data Set

Commercially available

An analysis of which commercially-available compounds are available has been done, and several compounds purchased and evaluated. OSM-S-72 to OSM-S-80, they were all not potent.

Other Sources (e.g. Academic Labs)

Azaindoles - doi:10.1016/j.bmcl.2009.03.034

Functionalised sulphonamides - doi: 10.1002/qsar.200420038

2,4-Diaminothienopyrimidines - dx.doi.org/10.1021/jm401760c

Purines and 7‑Deazapurines - doi: 10.1021/acs.jmedchem.5b00931

Thienopyridines - 10.1021/jm0510979

Thienopyridines - dx.doi.org/10.1016/j.ejmech.2015.11.012

The compound used in several control experiments lacking the sulfonamide, OSM-S-123, which is inactive against the parasite, has other biological activity of its own.

Aromatic sulfonamides similar to OSM-S-106 - DOI: 10.1021/acs.jmedchem.5b01771, https://doi.org/10.1016/j.ijpddr.2017.01.003

Periodic searches of available near neighbours should be made, e.g. this one.