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LINC diffusion MRI – X-ray pipeline 🧠🔗🩻

Supplementary material for the LINC diffusion MRI – X-ray paper.

Preprint

This work is currently available on bioRXiv as a preprint:

https://www.biorxiv.org/content/10.64898/2026.04.02.716198

Gallery

The data can be opened in the web browser from the LINC Gallery:

https://gallery.lincbrain.org/mri-xray

Scripts

This work has required the use of a few Python tools:

Repository Usecase
stack-to-chunk Conversion of a series of 2D images to a 3D volume stored as an OME-Zarr
ngregister Register with an affine transform using a set of hotkeys within Neuroglancer (optimal for large multiscale datasets)
segment_properties_for_neuroglancer Generate the segmentation properties for the Neuroglancer precomputed format to add metrics and a colormap to the segmentation layer
freesurfer Suite of processing tools for 3D imaging data, initially focused on MRI and the NIfTI file format
nitorch (Yet another) suite of processing tools for 3D imaging data, initially focused on MRI and the NIfTI file format
ngtools Web browser-based data viewer with an extensive set of utilities
tirl Registration library; cf. doi:10.1016/j.neuroimage.2022.119792.

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Supplementary material for the LINC diffusion MRI – X-ray paper

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