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Change in eRegulons filtering for Heatmap_dotplot #143

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Change in eRegulons filtering for Heatmap_dotplot #143

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69ab31c
Update dotplot.py
adrdufour Apr 17, 2023
121ff78
Merge branch 'aertslab:main' into main
adrdufour Aug 23, 2023
3eb4ce7
Update dotplot.py
adrdufour Aug 23, 2023
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16 changes: 10 additions & 6 deletions src/scenicplus/plotting/dotplot.py
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Original file line number Diff line number Diff line change
Expand Up @@ -102,10 +102,10 @@ def _find_idx(l, e):
size_matrix = size_matrix[color_matrix_features[2]]

if subset_eRegulons is not None:
#change to TF names
subset_eRegulons = [x.split('_')[0] for x in subset_eRegulons]
size_matrix = size_matrix[[x for x in size_matrix if x.split('_')[0] in subset_eRegulons]]
color_matrix = color_matrix[[x for x in color_matrix if x.split('_')[0] in subset_eRegulons]]
#filter eRegulon
subset_eRegulons = [x.split('_(')[0] for x in subset_eRegulons]
size_matrix = size_matrix[[x for x in size_matrix if x.split('_(')[0] in subset_eRegulons]]
color_matrix = color_matrix[[x for x in color_matrix if x.split('_(')[0] in subset_eRegulons]]

if scale_size_matrix:
size_matrix = (size_matrix - size_matrix.min()) / (size_matrix.max() - size_matrix.min())
Expand Down Expand Up @@ -204,8 +204,12 @@ def heatmap_dotplot(
order = pd.concat([idx_max[idx_max == x] for x in tmp.index.tolist() if len(plotting_df[plotting_df == x]) > 0]).index.tolist()
plotting_df['eRegulon_name'] = pd.Categorical(plotting_df['eRegulon_name'], categories = order)
plotnine.options.figure_size = figsize
#check repressor availability
plotting_df['repressor_activator'] = ['activator' if '+' in n.split('_')[1] and 'extended' not in n or '+' in n.split('_')[2] and 'extended' in n else 'repressor' for n in plotting_df['eRegulon_name']]
repressor_availability = 'repressor' in plotting_df['repressor_activator']
if not repressor_availability:
split_repressor_activator = False
if split_repressor_activator:
plotting_df['repressor_activator'] = ['activator' if '+' in n.split('_')[1] and 'extended' not in n or '+' in n.split('_')[2] and 'extended' in n else 'repressor' for n in plotting_df['eRegulon_name']]
if orientation == 'vertical':
plot = (
ggplot(plotting_df, aes('index', 'eRegulon_name'))
Expand All @@ -218,7 +222,6 @@ def heatmap_dotplot(
+ geom_point(
mapping = aes(size = 'size_val'),
colour = "black")
+ theme(axis_text_x=element_text(rotation=90, hjust=1))
+ theme(axis_title_x = element_blank(), axis_title_y = element_blank()))
elif orientation == 'horizontal':
plot = (
Expand Down Expand Up @@ -252,6 +255,7 @@ def heatmap_dotplot(
+ geom_point(
mapping = aes(size = 'size_val'),
colour = "black")
+ theme(axis_text_x=element_text(rotation=90, hjust=1))
+ theme(axis_title_x = element_blank(), axis_title_y = element_blank()))
if save is not None:
plot.save(save)
Expand Down