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[DO NOT MERGE] eval #3533 i:1: Add articular cartilage zonal chondrocyte cell types (opencode/openai/gpt-5.4, .)#593

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[DO NOT MERGE] eval #3533 i:1: Add articular cartilage zonal chondrocyte cell types (opencode/openai/gpt-5.4, .)#593
cmungall wants to merge 2 commits into
eval-base-issue-3533from
scribe-v1-ai4curation-cl-agent-config-v3-.-openai-gpt-5.4-iter1-issue-3533

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⚠️ EVALUATION ONLY - DO NOT MERGE ⚠️

Original Issue

#3533: Add articular cartilage zonal chondrocyte cell types

Original PR (human solution)

#3571: Add articular cartilage zonal chondrocyte cell types

Agent Commits

  • Add zonal articular chondrocyte terms

Note: This PR diff shows ONLY the agent's changes. The baseline is eval_base_branch.

Agent Response - PR Comments

Added four new subclasses of articular chondrocyte to represent the major depth-dependent zones of articular cartilage:

  • CL:9900000 superficial zone articular chondrocyte
  • CL:9900001 middle zone articular chondrocyte
  • CL:9900002 deep zone articular chondrocyte
  • CL:9900003 calcified zone articular chondrocyte

What changed:

  • Added new class declarations for the four CL_99xxxxx terms.
  • Added labels, textual definitions, contributor ORCID, and terms:date annotations.
  • Added the requested zonal synonyms where applicable:
    • transitional zone articular chondrocyte for middle zone articular chondrocyte
    • radial zone articular chondrocyte for deep zone articular chondrocyte
  • Placed all four terms under articular chondrocyte (CL:1001607 in this file).
  • Added marker-based axioms only where they were well supported by the referenced literature and already fit existing CL modeling style:
    • PRG4 for superficial zone articular chondrocyte
    • COL10A1 for deep zone articular chondrocyte
    • COL10A1 for calcified zone articular chondrocyte

Rationale:

  • The issue requested conservative, well-established zonal subclasses for articular cartilage.
  • I used a minimal modeling approach because specific UBERON classes for each articular cartilage zone were not readily available from the ontology lookup performed here.
  • The definitions reflect the established morphology, matrix environment, and functional distinctions across superficial, middle/transitional, deep/radial, and calcified zones.

References used during curation:

  • PMID:41226342
  • PMID:18455690
  • PMID:23124445
  • PMID:23015907

Validation performed:

  • Reviewed the existing articular chondrocyte neighborhood in src/ontology/cl-edit.owl for parent consistency.
  • Checked the exact git diff to confirm the change was limited to the intended ontology additions.
  • Ran robot convert -i src/ontology/cl-edit.owl -o /tmp/opencode/cl-edit.ofn successfully as a syntax-level validation.

Completed checklist:

  • Read imported issue context
  • Confirmed parent term and existing neighboring terms
  • Reviewed cited PubMed sources available in this environment
  • Added four new CL_99xxxxx terms with references and metadata
  • Validated the edited ontology file
  • Committed only src/ontology/cl-edit.owl

🤖 Generated by opencode agent

  • Runtime: opencode
  • Model: openai/gpt-5.4
  • Agent config: ai4curation/cl-agent-config@v3:.
  • Iteration: 1
  • Run: View workflow run

Agent Response - Issue Comments

Implemented the requested zonal articular chondrocyte terms and committed the changes locally. Ready for review in PR #.


🤖 Generated by opencode agent

  • Runtime: opencode
  • Model: openai/gpt-5.4
  • Agent config: ai4curation/cl-agent-config@v3:.
  • Iteration: 1
  • Run: View workflow run

Experiment Config

Parameter Value
Model openai/gpt-5.4
Agent config ai4curation/cl-agent-config@v3:.
Iteration 1
URL prefix https://href.li/?
Base branch eval-base-issue-3533

See workflow artifacts for full agent trace.

github-actions Bot added 2 commits May 17, 2026 01:06
Signed-off-by: github-actions[bot] <github-actions[bot]@users.noreply.github.com>
Model: openai/gpt-5.4
Issue repo: obophenotype/cell-ontology
Agent config: ai4curation/cl-agent-config@v3:.
Iteration: 1

Artifacts: https://github.com/ai4curation/eval-ont-agent-cl/actions/runs/25977506170#artifacts
@cmungall

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📋 Traces: traces/25977506170

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