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[DO NOT MERGE] eval #3479 i:1: [Text def] Revise textual definition and medial ganglionic eminence derived interneuron and add markers (opencode/openai/gpt-5.5, .)#604

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[DO NOT MERGE] eval #3479 i:1: [Text def] Revise textual definition and medial ganglionic eminence derived interneuron and add markers (opencode/openai/gpt-5.5, .)#604
cmungall wants to merge 2 commits into
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scribe-v1-ai4curation-cl-agent-config-v3-.-openai-gpt-5.5-iter1-issue-3479

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⚠️ EVALUATION ONLY - DO NOT MERGE ⚠️

Original Issue

#3479: [Text def] Revise textual definition and medial ganglionic eminence derived interneuron and add markers

Original PR (human solution)

#3526: #3479 Added Markers for Medial Ganglionic Eminence neuron

Agent Commits

  • Revise MGE-derived interneuron definition

Note: This PR diff shows ONLY the agent's changes. The baseline is eval_base_branch.

Agent Response - PR Comments

Updated CL_4023063 (medial ganglionic eminence derived interneuron) to address issue #3479.

Changes made:

  • Revised the textual definition to mention development from the medial ganglionic eminence and characteristic expression of MGE lineage markers NKX2-1 and LHX6.
  • Added a term_tracker_item annotation linking CL_4023063 back to issue #3479.
  • Added marker expression axioms using existing ontology patterns:
  • RO_0002292 some PR_000011241 for NKX2-1.
  • RO_0002292 some PR_000032533 for LHX6.

Rationale:

  • The previous definition only stated derivation from the medial ganglionic eminence and did not include markers, while the issue requested a textual definition revision and marker additions.
  • NKX2-1 and LHX6 are already referenced in nearby CL content as hallmark indicators of MGE-derived interneurons, and the corresponding PR identifiers were confirmed before use.
  • The existing genus-differentia logical definition was preserved, with marker expression added as subclass axioms to avoid changing the core equivalence classification.

Checklist completed:

  • Checked the existing CL_4023063 axioms and nearby MGE/CGE-derived interneuron terms.
  • Checked consistency of the proposed marker relation pattern against existing RO_0002292 marker axioms in cl-edit.owl.
  • Confirmed PR identifiers for NKX2-1 and LHX6 before adding marker axioms.
  • Ran robot convert -i src/ontology/cl-edit.owl -o /tmp/opencode/cl-edit-check.owl successfully.
  • Ran git diff --check -- src/ontology/cl-edit.owl successfully.

Note:

  • Attempted to fetch the cited DOI with aurelian fulltext DOI:10.1101/2022.10.12.511898, but aurelian is not installed in this environment.

Signed-off-by: GitHub Copilot


🤖 Generated by opencode agent

  • Runtime: opencode
  • Model: openai/gpt-5.5
  • Agent config: ai4curation/cl-agent-config@v3:.
  • Iteration: 1
  • Run: View workflow run

Agent Response - Issue Comments

Changes committed in PR #.


🤖 Generated by opencode agent

  • Runtime: opencode
  • Model: openai/gpt-5.5
  • Agent config: ai4curation/cl-agent-config@v3:.
  • Iteration: 1
  • Run: View workflow run

Experiment Config

Parameter Value
Model openai/gpt-5.5
Agent config ai4curation/cl-agent-config@v3:.
Iteration 1
URL prefix https://href.li/?
Base branch eval-base-issue-3479

See workflow artifacts for full agent trace.

github-actions Bot added 2 commits May 17, 2026 04:35
Update CL_4023063 with a richer textual definition, issue tracker link, and marker expression axioms for NKX2-1 and LHX6.

Signed-off-by: GitHub Copilot <copilot@github.com>
Model: openai/gpt-5.5
Issue repo: obophenotype/cell-ontology
Agent config: ai4curation/cl-agent-config@v3:.
Iteration: 1

Artifacts: https://github.com/ai4curation/eval-ont-agent-cl/actions/runs/25981389719#artifacts
@cmungall

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📋 Traces: traces/25981389719

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