Pseudotime Analysis of embryonic mouse islets to uncover the role of Nnat in establishing mature beta cell populations.
This analysis was done for the study titled: Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
This analysis depends on the Seurat v4.3 and Monocle 3 packages in R.
The datasets used were acquired from the following studies:
- Embryonic islets: https://www.nature.com/articles/s41467-018-06176-3
- Adult islets: https://www.sciencedirect.com/science/article/pii/S2212877822001648?via%3Dihub
