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New provider for inn: dotad#1730

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bgyori merged 2 commits into
biopragmatics:mainfrom
kanghosaeyo:dotad
Oct 30, 2025
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New provider for inn: dotad#1730
bgyori merged 2 commits into
biopragmatics:mainfrom
kanghosaeyo:dotad

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@kanghosaeyo

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This PR curates a new publication about DOTAD, the first database dedicated exclusively to therapeutic antibody developability information. DOTAD aggregates therapeutic antibody sequence data with comprehensive developability metrics including aggregation propensity, immunogenicity risk, stability, and manufacturability to support computational modeling and therapeutic antibody development. The database uses standardized INN as identifiers for therapeutic antibodies.

https://pubmed.ncbi.nlm.nih.gov/38530613/
https://i.uestc.edu.cn/DOTAD

Comment thread src/bioregistry/data/bioregistry.json Outdated
"year": 2024
}
],
"uri_format": "https://i.uestc.edu.cn/DOTAD/detail.html?INN=$1"

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Could this just be a search for international nonproprietary names (INNs)? Those are string literals and I don’t think qualify to get registered as an identifier space.

@bgyori

bgyori commented Oct 19, 2025

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I agree with #1730 (comment), this is a potentially useful resource but it sees to be resolving INNs. INNs come from a published list by the WHO so can be considered a closed vocabulary and we already have a prefix inn for it, so this could be curated as a provider for inn.

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codecov Bot commented Oct 26, 2025

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Codecov Report

✅ All modified and coverable lines are covered by tests.
✅ Project coverage is 45.55%. Comparing base (8950e70) to head (546e509).
⚠️ Report is 864 commits behind head on main.

Additional details and impacted files
@@            Coverage Diff             @@
##             main    #1730      +/-   ##
==========================================
+ Coverage   42.51%   45.55%   +3.04%     
==========================================
  Files         117      127      +10     
  Lines        8327     9582    +1255     
  Branches     1963     1634     -329     
==========================================
+ Hits         3540     4365     +825     
- Misses       4582     4924     +342     
- Partials      205      293      +88     

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@bgyori bgyori changed the title New prefix: dotad New provider for inn: dotad Oct 27, 2025
@bgyori bgyori merged commit 1aa39a5 into biopragmatics:main Oct 30, 2025
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@kanghosaeyo kanghosaeyo deleted the dotad branch October 30, 2025 21:23
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3 participants