Chemistry Knowledge Base

A persistent, LLM-maintained chemistry wiki and structured knowledge base for:

• reaction families
• mechanisms
• heuristic rules
• exceptions
• substrate classes
• reagents and catalysts
• conditions
• failure modes
• green chemistry insights
• synthesis planning heuristics

This repository uses a Karpathy-style “compiled wiki” workflow: raw sources are ingested into a structured, cross-linked markdown wiki, with matching structured database support.

Core files

• overview.md — high-level description of the knowledge base
• index.md — content map of all important pages
• log.md — append-only record of ingests, queries, and maintenance
• AGENTS.md — workflow and operating rules for the LLM maintaining the wiki

Repository layers

• raw/ — immutable source materials
• topic folders — maintained wiki pages
• schema/ — conventions and policies
• db/ — structured schema
• scripts/ — optional automation helpers