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Original file line number Diff line number Diff line change
Expand Up @@ -1667,8 +1667,13 @@ Default stratifications to all observers should include scenario and input draw.
* Confirm RR values for hemoglobin exposures <40 are equal to the RR value for a hemoglobin exposure of 40
* Confirm that artifact RR values match expectation
* Confirm that RR values for hemoglobin exposures above the TMREL vary according to the input data
-
-
- * Slight overestimation of maternal sepsis incidence, particularly in Nigeria. Mean values are generally within 10% of target otherwise. Significant draw-level variation, with underestimation of lower draws and overestimation of higher draws.
* Hemoglobin exposure appropriately modifies maternal disorder incidence but not mortality
* RR values for hemoglobin exposures <40 equal that of hemoglobin exposure equal to 40
* Artifact RR values match expectation
* RR values for hemoglobin exposures >TMREL vary according to input data
- * `Model 13.1 maternal checks notebook <https://github.com/ihmeuw/vivarium_research_mncnh_portfolio/blob/main/verification_and_validation/model_13.1_maternal_checks.ipynb>`_
* `Model 13.1 interactive sim notebook <https://github.com/ihmeuw/vivarium_research_mncnh_portfolio/blob/main/verification_and_validation/model_13.1_interactive_simulation_hemoglobin.ipynb>`_
* - 13.2
- * Check late neonatal all-cause mortality risk and cause-specific mortality risks;
expected change is small but should be in the direction of better verification to GBD
Expand Down Expand Up @@ -1787,18 +1792,18 @@ Default stratifications to all observers should include scenario and input draw.
- Explanation
- Action plan
- Timeline
* - RR values for hemoglobin < 40 g/L not as expected
- All hemoglobin exposures less than 40 g/L should be assigned the RR for the 40 g/L exposure
- Hussain to update implementation accordingly
- For 13.1
* - RR values for hemoglobin exposures above the TMREL all equal 1
- They should be able to match input data for values not equal to 1 (greater than lower than one are both okay)
- Hussain to update implementation accordingly
- For 13.1
* - Miscalibration of maternal hemorrhage and sepsis incidence rates
- Due to non-location-specific hemoglobin PAF value
- Hussain to update
- For 13.1
* - Miscalibration of maternal sepsis incidence rates, particularly for Nigeria
- Thought to be due to using the fatal PAF from GBD applied to incidence and/or the location-aggregated PAF for our modeled locations which are not most detailed locations
- Update to custom-calculated PAF and reassess
- TBD
* - Issue with LBWSG PAF calculation for the late neonatal age group
- See the summary in the model 12.1.1 run request
- Hussain to update and rerun, Ali to do independent replication of PAF calculation verification
- Model 12.1.1
* - Some miscalibration of all-cause mortality for late neonatal females
- Could be due to random noise given that this is the demographic with the lowest mortality rates and therefore smallest counts
- Rerun with larger population size?
- TBD
* - Late neonatal mortality due to preterm birth slightly underestimated and other-causes mortality may be slightly overestimated (though within 10%)
- Unknown -- possibly related to negative other causes mortality in Pakistan and Nigeria.
- One possible cause addressed in model 13.3
Expand Down