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EMMo

EMMo (Expectation-Maximization-based Motif finder) is Python toolkit for training and exploring unsupervised methods for:

  • peptide-MHC binding motif identification,
  • deconvolution of multi-allelic data, and
  • peptide-MHC binding/presentation prediction.

The documentation can be found here.

Installation

Please refer to the following documentation page for installation steps: Installation

Overview

After installation, you can list all available commands by running

emmo --help

For the full documentation of a specific command you can run:

emmo {command} --help

All the Python code of the project can be found in the emmo directory and the main entrypoint is the file emmo/main.py.

If you want to learn more about the implemented deconvolution and prediction methods, check out the explanations for the MHC-II expectation-maximization algorithm and the MHC-II binding predictors.

For additional documentation (usage and explanations) you can check the project's documentation. To contribute to this repository, check the Contributing section.

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Unsupervised method for mhc2 motif deconvolution based on MoDec

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