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BIRDMAn Manuscript Analyses

Analysis code, processed data, and notebooks accompanying the BIRDMAn (Bayesian Inferential Regression for Differential Microbiome Analysis) manuscript.

About

BIRDMAn is a framework for fitting Bayesian differential abundance models to microbiome count data, built on top of CmdStanPy. This repository contains the end-to-end analyses used to evaluate BIRDMAn in the manuscript, including the scripts used to fit models on a SLURM cluster, the processed input data, and the Jupyter notebooks that generate the manuscript figures. BIRDMAn itself is available at biocore/birdman.

Installation

Runtime dependencies include birdman, cmdstanpy, biom-format, arviz, pandas, numpy, and matplotlib. We suggest installing cmdstanpy from conda-forge.

Citation

If you use this code or the processed data, please cite the BIRDMAn manuscript:

Maintainers

  • Gibraan Rahman — original author (gibsramen@gmail.com)
  • Lucas Patel — co-maintainer (lpatel@ucsd.edu)
  • Yang Chen — co-maintainer (yac027@ucsd.edu)

License

  • Code (src/, scripts/, notebooks/): BSD 3-Clause — see LICENSE.
  • Processed data (data/): CC0 1.0 Universal Public Domain Dedication — see data/LICENSE.

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