risk_calc

Calculate risk from 23andMe raw data

Live at:

https://lorenasandoval88.github.io/risk_calc/

Sample 23 and Me raw data files here: https://my.pgp-hms.org/public_genetic_data?data_type=23andMe

PRS background: https://www.illumina.com/content/dam/illumina/gcs/assembled-assets/marketing-literature/polygenic-risk-score-application-note-m-gl-00103/polygenic-risk-score-application-note-m-gl-00103.pdf

Tutorial: a guide to performing polygenic risk score analyses https://pubmed.ncbi.nlm.nih.gov/32709988/

API endpoints: https://www.pgscatalog.org/score/ https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/ https://doi.org/ https://rest.ensembl.org/variation/human/ https://www.snpedia.com/index.php/ https://myvariant.info/v1/variant/