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mainframe-official

inspiration from owl_posting

The Mission

Mainframe asks a simple question: could bittensor be used for generalized scientific compute? We at Macrocosmos believe so.

"Rational simulation-guided design of atomic systems has been a dream of researchers across the chemical sciences for decades. Enabling rapid and performant experimentation to experts would unlock massive potential to accelerate chemical science" Mann et al. 2025

For decentralized science to succeed, we need:

  1. Industry/Research collaboration
  2. Well defined metrics of success

Our Principles

  • fast
  • accurate
  • scalable
  • reliable simulation

Our Focus

  • molecular dynamics
  • material propery prediction
  • model training

Our Goals

  • academic papers with research groups
  • revenue generating pipelines

Our Accomplishments (last updated April 30th, 2025)

  1. the first desci subnet on bittensor ✅
  2. professional and revenue generating collaboration with Rowan Scientific to build DTF pipelines on sn25 ✅

License

This repository is licensed under the MIT License.

# The MIT License (MIT)
# Copyright © 2024 Yuma Rao
# Copyright © 2024 Macrocosmos AI

# Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated
# documentation files (the “Software”), to deal in the Software without restriction, including without limitation
# the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software,
# and to permit persons to whom the Software is furnished to do so, subject to the following conditions:

# The above copyright notice and this permission notice shall be included in all copies or substantial portions of
# the Software.

# THE SOFTWARE IS PROVIDED “AS IS”, WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO
# THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION
# OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
# DEALINGS IN THE SOFTWARE.