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mandhri/README.md

Hi, I'm Mandhri! πŸ‘‹

🧬 Bioinformatician @ ARMI, Monash University

DNA Methylation β€’ RNA-seq β€’ Proteomics β€’ Multi-Omics Integration

πŸ“ Australia β€’ πŸ“§ mandhri.abeysooriya@gmail.com β€’ πŸ”— LinkedIn


πŸ‘©πŸ»β€πŸ’» About me

PhD in Bioinformatics & Biostatistics (Deakin, 2025) | M.Sc. Bioinformatics I'm a bioinformatician passionate about extracting biological meaning from large, complex genomic datasets. I specialise in designing and executing end-to-end analysis workflows across DNA methylation, bulk RNA-seq, proteomics, and metabolomics, with a focus on identifying robust molecular signatures in heterogeneous populations.

I mostly work in R and Bash for reproducible bioinformatics workflows. Recently, I'm shifting more into Python and AI engineering to build scalable analysis tools and automation.


Tech Stack

Languages



Core engineering



Workflow + compute


Featured Projects

Project What it is Tools
DNA Methylation / EWAS QC, filtering, batch correction, EWAS/DMRs, pathway enrichment analysis interpretation R, python, bash
Bulk RNA-seq Pipelines FASTQ β†’ QC β†’ alignment/quant β†’ DE β†’ reporting Snakemake / Nextflow, R
Proteomics + Metabolomics Differential analysis, missingness-aware workflows, pathway enrichment analysis R, python
Multi-omics Integration Harmonising omics layers for robust signatures/subtypes R, HPC, Bash

Snake animation

profile views

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  1. RNA-Seq RNA-Seq Public

    Learning RNA-Seq from scratch

    Shell

  2. airway-glucocorticoid-rnaseq airway-glucocorticoid-rnaseq Public

    Glucocorticoid response signature in human airway cells (discovery + reproducibility)

    Python

  3. WGS-variant-callling---HPC-friendly-workflow WGS-variant-callling---HPC-friendly-workflow Public

    Shell

  4. scRNA_Analysis scRNA_Analysis Public

  5. Multi-Omics-Cancer-Subtype-Discovery Multi-Omics-Cancer-Subtype-Discovery Public

    Jupyter Notebook