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Running P2 solo with two flowcells on memory capped at 16gb on a GV100

Status: Open.

#1573 In nanoporetech/dorado;

· lborcard opened on Feb 13, 2026

Demultiplexing asymmetric barcodes (10 left and 96 right) with Dorado -- is this possible?

barcodeIssues related to barcodingIssues related to barcoding

questionIssue is a questionIssue is a question

Status: Open.

#1572 In nanoporetech/dorado;

· margaretc-ho opened on Feb 10, 2026

Does dorado demux support two rounds of demux?

barcodeIssues related to barcodingIssues related to barcoding

questionIssue is a questionIssue is a question

Status: Open.

#1571 In nanoporetech/dorado;

· billytcl opened on Feb 9, 2026

CUDA error: out of memory

polishIssues related to polishingIssues related to polishing

Status: Open.

#1570 In nanoporetech/dorado;

· 1AoB opened on Feb 9, 2026

Unclear state of duplex demultiplexing

documentationImprovements or additions to documentationImprovements or additions to documentation

Status: Open.

#1569 In nanoporetech/dorado;

· hjarnek opened on Feb 5, 2026

sup@5.2.0 basecalled reads lower quality than sup@5.0.0

Status: Open.

#1565 In nanoporetech/dorado;

· samuelmontgomery opened on Jan 27, 2026

Barcode trimming is overly aggressive

Status: Open.

#1564 In nanoporetech/dorado;

· jts opened on Jan 24, 2026

Output folder of demux incomprehensible

Status: Open.

#1563 In nanoporetech/dorado;

· stefandiederich opened on Jan 23, 2026

Inconsistent Poly(A) Tail Detection between Dorado versions

polyAIssue related to polyA tail estimationIssue related to polyA tail estimation

Status: Open.

#1562 In nanoporetech/dorado;

· nemitheasura opened on Jan 23, 2026

Systematic evaluation of computational tools for RNA modification detection

Status: Open.

#1560 In nanoporetech/dorado;

· SuhasSrinivasan opened on Jan 22, 2026

dorado polish - RAM of 768 GB not sufficient

polishIssues related to polishingIssues related to polishing

Status: Open.

#1559 In nanoporetech/dorado;

· colindaven opened on Jan 22, 2026

Interpreting output of dorado demux using custom barcodes at both ends

barcodeIssues related to barcodingIssues related to barcoding

documentationImprovements or additions to documentationImprovements or additions to documentation

Status: Open.

#1556 In nanoporetech/dorado;

· Kyung-TaeLee opened on Jan 19, 2026