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Hi,
Would you like to add the option to read an alignment bam/cram file from ftp/https/s3? I could open a PR, but I wanted to check first.
Additionally, I wonder why you still consider cram to be unstable and advice against it. Setting the CRAM_OPT_REQUIRED_FIELDS could greatly speed up parsing cram files, depending on which fields you need to decode (see for example https://brentp.github.io/post/cram-speed/).
Wouter