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In your documentation (chapter 1.13), you have:
-a ${norm_pileup_1}.gz \
-a ${norm_pileup_2}.gz \
-b ${tumor_pileup_1}.gz \
-b ${tumor_pileup_2}.gz \
and I've checked in another issue that you clarified that the effect size is something like prop_a-prop_b, but we generally like using the control as the baseline, so I suggest changing the documentation to the following or calculate it as prop_b-prop_a instead.
-a ${tumor_pileup_1}.gz \
-a ${tumor_pileup_2}.gz \
-b ${norm_pileup_1}.gz \
-b ${norm_pileup_2}.gz \
I only found this out as I was comparing another method and found that we had inverse correlations.
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documentationImprovements or additions to documentationImprovements or additions to documentation