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pattern_name: abnormallyDecreasedEfficacyOfBiologicalProcess
pattern_iri: http://purl.obolibrary.org/obo/upheno/patterns-dev/abnormallyDecreasedEfficacyOfBiologicalProcess.yaml
description: "An abnormally decreased efficacy (reduced ability to produce an output of normal amount and/or quality*) of a biological process compared to controls. *Here 'quality' refers specifically to the 'goodness', 'properness', or 'adequateness' of the output (as opposed to any characteristic in general) and 'output' can mean a particular physical entity (like metabolite as a product of a metabolic process) or state (or configuration) of a physical entity (like the fitness or health of a cell). This phenotype is usually inferred from more direct observations; for example, blood glucose levels may be measured by a colorimetric assay applied to a blood sample, which then is used to infer that blood glucose is high, low, or unstable, which can then itself be used to infer that blood glucose homeostasis is defective or has reduced efficacy."

contributors:
- https://orcid.org/0000-0001-9076-6015

classes:
decreased efficacy: PATO:0015003
abnormal: PATO:0000460
biological process: GO:0008150

relations:
inheres_in: RO:0000052
has_modifier: RO:0002573
has_part: BFO:0000051

annotationProperties:
exact_synonym: oio:hasExactSynonym

vars:
biological_process: "'biological process'"

name:
text: "decreased efficacy of %s"
vars:
- biological_process

annotations:
- annotationProperty: exact_synonym
text: "defective %s"
vars:
- biological_process

def:
text: "Decreased efficacy of %s."
vars:
- biological_process

equivalentTo:
text: "'has_part' some ('decreased efficacy' and ('inheres_in' some %s) and ('has_modifier' some 'abnormal'))"
vars:
- biological_process