Merck Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc.

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78 repositories

forestly
Public
Interactive forest plot for adverse events analysis
R
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GNU General Public License v3.0
•4•17•3•0•Updated Jan 16, 2026Jan 16, 2026
metalite.ae
Public
An R package for standard adverse events analysis
metadata clinical-trials r-package cdisc
R
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GNU General Public License v3.0
•4•24•4•2•Updated Jan 15, 2026Jan 15, 2026
metalite.sl
Public
An R package designed for the analysis & reporting of subject baseline characteristics in clinical trials.
R
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GNU General Public License v3.0
•1•1•14•2•Updated Jan 15, 2026Jan 15, 2026
gsDesign2
Public
Group Sequential Design Under Non-Proportional Hazards
R
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GNU General Public License v3.0
•8•28•4•1•Updated Jan 13, 2026Jan 13, 2026
boxly
Public
Interactive box plot for clinical trial analysis
R
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GNU General Public License v3.0
•2•13•6•0•Updated Jan 9, 2026Jan 9, 2026
r2rtf
Public
Easily Create Production-Ready Rich Text Format (RTF) Table and Figure
R
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GNU General Public License v3.0
•22•83•0•0•Updated Jan 9, 2026Jan 9, 2026
rtdpy
Public
Residence Time Distribution modeling in Python.
python residence-time-distribution process-development
Python
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MIT License
•8•8•0•0•Updated Dec 18, 2025Dec 18, 2025
simtrial
Public
Clinical trial simulation for time-to-event endpoints
R
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GNU General Public License v3.0
•11•30•3•1•Updated Nov 21, 2025Nov 21, 2025
GoNoGo
Public
R
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GNU General Public License v3.0
•0•0•0•0•Updated Oct 3, 2025Oct 3, 2025
metalite
Public
An R package to create metadata structure for ADaM data analysis and reporting
metadata clinical-trials r-package cdisc
R
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GNU General Public License v3.0
•7•16•3•0•Updated Sep 17, 2025Sep 17, 2025
wpgsd
Public
Weighted parametric group sequential design
R
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GNU General Public License v3.0
•3•3•4•0•Updated Sep 4, 2025Sep 4, 2025
gMCPLite
Public
Lightweight graph-based multiple comparison procedures
R
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GNU General Public License v3.0
•3•13•0•0•Updated Aug 26, 2025Aug 26, 2025
AlgebraicAgents.jl
Public
A lightweight framework to enable hierarchical, heterogeneous dynamical systems co-integration. Batteries included!
julia julia-language dynamical-systems differential-equations stochastic-processes
Julia
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Other
•3•22•0•1•Updated Aug 20, 2025Aug 20, 2025
ReactiveDynamics.jl
Public
A Julia package that implements a category of reaction (transportation) network-type dynamical systems.
optimization decision-making julia-language reaction-network differential-equations strategic-planning scientific-machine-learning
Julia
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Other
•3•18•1•1•Updated Aug 18, 2025Aug 18, 2025
Sapiens
Public
Sapiens is a human antibody language model based on BERT.
embeddings antibody language-model bert sapiens
Jupyter Notebook
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MIT License
•20•68•1•0•Updated May 14, 2025May 14, 2025
BioPhi
Public
BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody sequence design.
antibody oasis humanization sapiens humanness
Python
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MIT License
•59•222•39•1•Updated May 13, 2025May 13, 2025
matcher-mmpdb
Public
Python
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MIT License
•2•7•0•0•Updated Mar 27, 2025Mar 27, 2025
ChemicalSpaceGeneration
Public
Jupyter Notebook
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Other
•5•1•0•0•Updated Feb 28, 2025Feb 28, 2025
psm3mkv
Public
psm3mkv: A package to evaluate the fit and efficiency of three state oncology cost-effectiveness model structures
R
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GNU General Public License v3.0
•2•10•2•0•Updated Dec 18, 2024Dec 18, 2024
bgc-pipeline
Public
Jupyter Notebook
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MIT License
•1•12•2•0•Updated Dec 10, 2024Dec 10, 2024
CEEDesigns.jl
Public
A decision-making framework for the cost-efficient design of experiments, balancing the value of acquired experimental evidence and incurred costs.
decision-making julia-language experimental-design
Julia
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Other
•1•8•0•0•Updated Nov 22, 2024Nov 22, 2024
pkglite
Public
Compact Package Representations
package r clinical-trials packaging-tool ectd pharmaverse
R
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GNU General Public License v3.0
•4•30•5•0•Updated Nov 9, 2024Nov 9, 2024
AnNoBrainer
Public archive
0•0•0•0•Updated Aug 7, 2024Aug 7, 2024
puqsar
Public
Prediction Uncertainty for QSAR
Python
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GNU General Public License v3.0
•1•1•0•0•Updated Jul 13, 2024Jul 13, 2024
MolPROP
Public
fuses molecular language and graph representation for property prediction
Python
•5•22•0•0•Updated Jun 1, 2024Jun 1, 2024
ProbeDesign
Public
HTML
•2•1•0•0•Updated May 9, 2024May 9, 2024
mRNAid
Public
Jupyter Notebook
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Other
•13•15•10•0•Updated May 6, 2024May 6, 2024
.github
Public
0•0•0•0•Updated May 1, 2024May 1, 2024
Line-of-Therapy-Algorithm
Public
This is the Line of Therapy Algorithm, as described in the paper "Temporal phenotyping by mining healthcare data to derive lines of therapy for cancer" pending submission in the Journal of Biomedical Informatics.
Python
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GNU General Public License v3.0
•17•35•2•1•Updated Apr 29, 2024Apr 29, 2024
AbLEF
Public
Antibody Langauge Ensemble Fusion - fuses antibody structural ensemble and language representation for property prediction
Python
•4•13•2•0•Updated Apr 23, 2024Apr 23, 2024