Closes #292 add ader template

[jeffreyad]

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The following line requests to update the man pages by the "Man Pages" workflow.

/roxygenize

[github-actions]

Package	Line Rate	Health
admiralonco	97%	✔
Summary	97% (614 / 630)	✔

[Copilot]

Pull request overview

This pull request adds a new ADER (Exposure Response Data) template to the admiralonco package. The template is designed to create analysis datasets for exposure-response modeling by combining time-to-event data, response data, and various baseline covariates including demographics, vital signs, and laboratory values.

Changes:

• Added inst/templates/ad_ader.R template for creating ADER datasets with exposure-response variables, covariates, and baseline measurements

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[Copilot]

The template uses data("admiral_adsl") and data("admiral_adrs") which is inconsistent with other templates in this package that use data("adsl") and data("adrs_onco") respectively. This inconsistency may cause issues if these dataset names don't exist in the expected packages. Review other templates (e.g., inst/templates/ad_adtte.R line 20, inst/templates/ad_adrs.R line 22) for the correct dataset names to ensure consistency.

[jeffreyad]

@bundfussr and @manciniedoardo If I want to include adtte_onco as source, should it also be saved in {admiralonco}? Currently it is pulled from {pharmaverseadam}

[manciniedoardo]

Pulling from pharmaverseadam would introduce a circular dependency because pharmaverseadam itself has a dependency on admiralonco. So I would say yes.

[bundfussr]

I'm not sure. In the other templates we use the ADaM datasets from pharmaverseadam. Even in the vignettes we use them. So it shouldn't cause technical issues.

The only tricky scenario I'm aware of is when for example adrs_onco changes. In this case we would need to release admiralonco with the updated ADRS template, then release pharmaverseadam with the updated adrs_onco dataset, and finally recreate the admiralonco website to use the updated adrs_onco dataset in the ADTTE vignette.

Maybe we should remove admiral_adrs from admiralonco it seems that it isn't used anywhere.

[manciniedoardo]

ok, if that works then it's fine - personally i'd rather not have all these steps but final call is yours of course!

[jeffreyad]

By the way, I think even in ad_adtte.R the data("adrs_onco") is pulling from {pharmaverseadam} rather than the local admiral_adrs object.

[bundfussr]

Yes, I would use the datasets from pharmaverseadam. Whenever this causes issues in the future we can change it. But I think it's very unlikely.

[bundfussr]

@jeffreyad , could you create a vignette for these templates?

I think with a vignette it is easier for users to understand (and find) these templates.