Compare the results from eQuilibrator (component contribution) or group contribution methods with experimental results from nucleoside phosphorolysis

My "Farm of Ideas" is supposed to store ideas I would like to develop into scientific progress some day. This is the template for all ideas in this Farm.

Measuring the invisible: exploiting a two-substrate two-product equilibrium to determine the decomposition rate of one of the products

Generalized yields of coupled enzymatic reactions.

Finding thermodynamic cycles in the metabolism

Create an open database for the thermodynamics of enzyme-catalyzed reactions (and other metabolism relevant thermodynamic data)

It is possible to predict the spectrum of e.g. a nucleobase in a nucleoside-nucleobase conversion.

compare two-point UV/Vis spectroscopy read-out with spectral unmixing

When is it favorable to do two-step or one-pot coupled enzyme reactions?

When determining equilibrium constants of multi-substrate / multi-product reactions, their ratios affect the uncertainty of the result.