Investigating the impact of COVID infections on the blood-brain barrier using GSEA and GEO datasets. GEO datasets used: GSE167000 (Idnetification & Verification) GSE179923 (Verification)
Explore gene expression changes at the blood-brain barrier in response to COVID infections.
Performed Gene Set Enrichment Analysis (GSEA) using datasets obtained from GEO.
Identified gene expression patterns indicative of blood-brain barrier dysfunction in COVID-infected individuals.
- Python 3
- R
- GSEA software
Contributions and feedback are welcome! Please submit bug reports or feature requests via GitHub issues.
This project is licensed under the MIT License.
Special thanks to Dr Laura Harris (https://github.com/oesterei) for providing entire Python script (GSEA_Script.ipynb) that made the Analysis possible along with guidance and support throughout the project.
Work in progress.