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Working Memory Architecture and Demand (WoMAD) Model

This reposiroty will house the WoMAD model project code which is an extension of our previous work during the NMA ISP, called WMAD with a micropublication on Zenodo, titled "Parallel GNN-LSTM Model Predicting Working Memory Involvement during Language and Emotion Processing."

WoMAD is a modular neural network designed to analyze fMRI and BOLD time series data. The model uses spatiotemporal biosignals from task-based functional MRI datasets like the Human Connectome Project (HCP) to predict probability scores of node-based activity levels in the brain during tasks based on patterns of Working Memory (WM) activity in the brain.

WoMAD has two independent modules: Information flow and Core.

The information flow module follows the spatiotemporal activity of tasks in the data to creatae a 3D graph of the "moving activity" in the brain predicted in both unsupervised and supervised ways. The goal of the information flow module is to find the path of information through a brain as a task is being completed.

The core module is comprised of four submodules. First, the BOLD time series data is presented to a segmentation module to be labeled based on activity. The labeled output is then passed to two parallel submodules, a convolutional 4D network and an LSTM, which analyze the signals spatiotemporally and temporally, respectively. The final submodule is a fusion layer that combines ourputs from our parallel pair of submodules to produce two outputs: (a) A probability score of overall activity and (b) voxel-wise (or parcel-wise) probability scores of activity which will allow us to analyze the location of activity for the analyzed task and statistically predict the extent of WM involvement in a given task.

License

This project is licensed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.

See the LICENSE file for more details.

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