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@saha-project

Spatial Atlas of Human Anatomy (SAHA)

Open-science project to build a subcellular-resolution reference atlas of human organs using multimodal spatial omics and imaging.

SAHA Project – Spatial Atlas of Human Anatomy

Welcome to the official GitHub organization for the Spatial Atlas of Human Anatomy (SAHA), a multimodal reference of human tissues at subcellular resolution. We develop and release high-resolution spatial omics datasets, computational tools, and benchmarks to enable tissue-scale systems biology and clinical translation.

The SAHA project brings together spatial transcriptomics, proteomics, histology, and AI-based computational methods to chart the healthy and diseased human body in unprecedented detail.

  • Subcellular-resolution spatial profiling across gastrointestinal and immune tissues
  • Multi-modal datasets: CosMx SMI, MERFISH, spatial proteomics, histology, and clinical metadata
  • Applications in cancer, inflammation, and tissue microenvironment modeling
  • Open science collaboration across institutions

Key Repositories and Data

** currently waiting for a manuscript acceptance for a full release, but want you can access today: **

For project overviews, interactive figures, and publications, visit our site: https://saha-project.org.

All datasets are available through our website or directly via Zenodo

Here are some of our primary repositories:

  • saha – manuscript figures, data loaders, and core workflows
  • saha-maxfuse – multimodal integration of CosMx and histology
  • saha-scimap – spatial data analysis and visualization tools

For a full list, browse the organization repositories.

Publication

Our work is available as a preprint:

The Spatial Atlas of Human Anatomy (SAHA)
bioRxiv, 2025. In peer review.

Stay tuned for updates when the manuscript is accepted.

Get Involved

We welcome collaborators in spatial biology, machine learning, clinical research, and bioinformatics. If you're interested in contributing or proposing a collaboration:

Contact us via the website
File issues or pull requests in relevant repositories

License

Code in SAHA repositories is generally licensed under the MIT License, and data under CC BY 4.0. Controlled-tier data require a signed Data Use Agreement. Check individual repositories for specifics.


Maintained by the SAHA Consortium.

Popular repositories Loading

  1. SAHA SAHA Public

    Reproducible figure generation, data, and methods for the Spatial Atlas of Human Anatomy (SAHA) project.

    Jupyter Notebook 5

  2. saha-maxfuse saha-maxfuse Public

    Jupyter Notebook

  3. saha-scimap saha-scimap Public

    Jupyter Notebook

  4. Data_visualization Data_visualization Public

  5. .github .github Public

  6. saha-data-access saha-data-access Public

    Python

Repositories

Showing 7 of 7 repositories

People

This organization has no public members. You must be a member to see who’s a part of this organization.

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