Norms when subsetting 10X multiome dataset using WNN vignette

[sylestiel]

Hi,

Does subsetting of Seurat object when using WNN analysis of 10x Multiome, RNA + ATAC vignette require a repeat of SCT and LSI steps as well as the FindMultimodalNeighbors?

Thanks!

[kathbosc]

Hi all, I have a similar question.. What is the best practice after subsetting an integrated multiome dataset (RNA and ATAC) before running WNN again? Any recommendation is greatly appreciated! Thanks a lot in advance!