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@mass-a mass-a commented Sep 26, 2025

Name of the tool: pyUCell

Short description: pyUCell is a computational method for robust and scalable single-cell signature scoring. UCell signature scores, based on the Mann-Whitney U statistic, are robust to dataset size and heterogeneity, and their calculation is very fast and memory-efficient.

How does the package use scverse data structures (please describe in a few sentences): pyUCell relies on AnnData data structures and depends on scanpy. It can be integrated in existing scanpy pipelines and offers an alternative to scanpy.tl.score_genes()

  • The code is publicly available under an OSI-approved license
  • The package provides versioned releases
  • The package can be installed from a standard registry (e.g. PyPI, conda-forge, bioconda)
  • Automated tests cover essential functions of the package and a reasonable range of inputs and conditions [^1]
  • Continuous integration (CI) automatically executes these tests on each push or pull request [^2]
  • The package provides API documentation via a website or README[^3]
  • The package uses scverse datastructures where appropriate (i.e. AnnData, MuData or SpatialData and their modality-specific extensions)
  • I am an author or maintainer of the tool and agree on listing the package on the scverse website

Recommended

  • Please announce this package on scverse communication channels (zulip, discourse, twitter)

  • Please tag the author(s) these announcements. Handles (e.g. @scverse_team) to include are:

    • Zulip:
    • Discourse:
    • Mastodon:
    • Bluesky: @carmonation.bsky.social
    • Twitter: @carmonation
  • The package provides tutorials (or "vignettes") that help getting users started quickly

  • The package uses the scverse cookiecutter template.

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@mikkelnrasmussen mikkelnrasmussen left a comment

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Hi @mass-a,

Thanks for submitting pyUCell - it looks like a very nice tool! I've had a look at the package and everything looks good to me.

Best,
Mikkel

@mikkelnrasmussen mikkelnrasmussen merged commit 5304e85 into scverse:main Oct 1, 2025
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2 participants