nf-core/rnaseq runs bedtools genomecov and UCSC bedGraphToBigWig/bedClip. This is three sequential file-roundtrips per strand to produce bigWig files. A Rust BAM→bigWig writer (the bigWig format already has Rust implementations, e.g. bigtools) would collapse all three into the existing RustQC streaming pass.
nf-core/rnaseq runs
bedtools genomecovand UCSCbedGraphToBigWig/bedClip. This is three sequential file-roundtrips per strand to produce bigWig files. A Rust BAM→bigWig writer (the bigWig format already has Rust implementations, e.g.bigtools) would collapse all three into the existing RustQC streaming pass.