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The story so far
This project came about as a thought that I had whilst sitting in hospital waiting for test results from my son's lumbar puncture in late 2017. It ended up taking 48 hrs to return a negative result. At this stage I knew Nanopore sequencing was cheap and fast, and (back then) doable in hours. So why couldn't we easily get this sort of technology into hospitals? Why stop there, surely we could continue in the disruptive vein that ONT are paving and really democratise next-generation sequencing, providing it to the masses, think cheap 'off-the-shelf' parts that start to make this accessible to communities and developing countries. So that's what got the ball rolling, and it's been incredible seeing and meeting all the like-minded people on this journey to where we are now.
We have established fully operational Nanopore 'images' on both Nvidia Jetson Xavier NX and AGX boards in-house at ESR, New Zealand. Additionally, we have independent confirmation of the same set up working in Basel, Switzerland on a Xavier AGX. We also have confirmation on the older Jetson TX2 hardware from collaborators in Italy.
So currently we can provide a confirmed working list of components and software versions, all of which will be kept updated on GitHub repository.
We also have the exciting confirmation that adaptive sequencing is working on the Jetson Xavier AGX using the built in API in the current release of MinKnow. For more information on this see this Gist.
Our work was recently highlight in an article on genomics published by the New Zealand Herald. You can find the full story here.
"This tool is only limited by the imagination of those who use it – it falls upon us to find new ways of using it in different contexts."