Smoking Behavior Simulation Model

This repository contains all the code (but not the data) used for our smoking behavior simulation model.

The main files of interest are:

• simulation.py - The main code for the simulation behavior lives here
• uncertainty_analysis_create_params.py & uncertainty_analysis_do_runs.py - This code orchestrates the uncertainty analysis--the process of randomly varying simulation parameters so that we can see how simulation results look over a large number of slightly different runs.

Citation

If you use this work, please cite:

@article{mills-tapphughes2026
    doi = {10.1371/journal.pone.0342083},
    author = {Mills, Sarah D. AND Tapp Hughes, Nicholas AND Zhang, Yu AND Ribisl, Kurt M. AND Wiesen, Christopher A. AND Fan, Jiaqian AND Hassmiller Lich, Kristen},
    journal = {PLOS ONE},
    publisher = {Public Library of Science},
    title = {Development and validation of the Tobacco Use Individual-level Simulation and Tracking (TwIST) Model},
    year = {2026},
    month = {02},
    volume = {21},
    url = {https://doi.org/10.1371/journal.pone.0342083},
    pages = {1-17},
    number = {2},
}