Hello,
panelbuilder has some nice unmixing options that go beyond OLS. I haven't tried too much of it, but especially removing specific spectra from the data (e.g. an autofluorescence from single stain cells) seems interesting. I'll probably reproduce a lot of what they do in Python anyway, would you be interested in me adding that functionality to the package? Their special unmixing would add a torch dependency, but that could be treated as an optional dependency. (I could technically also implement it in pure numpy, but GPU support is pretty useful if the data get large.)
Greetings
Valentin
Hello,
panelbuilder has some nice unmixing options that go beyond OLS. I haven't tried too much of it, but especially removing specific spectra from the data (e.g. an autofluorescence from single stain cells) seems interesting. I'll probably reproduce a lot of what they do in Python anyway, would you be interested in me adding that functionality to the package? Their special unmixing would add a torch dependency, but that could be treated as an optional dependency. (I could technically also implement it in pure numpy, but GPU support is pretty useful if the data get large.)
Greetings
Valentin