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Releases: epam/Indigo

Indigo-1.43.0

13 May 18:42
cef4a11

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Features

  • #3526 - Update SDF and KET format to include information about preset phosphate position
  • #3525 - Expose ability to calculate fully expanded large molecule into chemical structures
  • #3562 – Add api to iterate through attachments points of S-groups of 'SUP' type
  • #3554 - Implement multi-threading in Bingo NoSQL substructure search

Bugfixes and improvements

  • #3307 - If the selected group is forming an n-agon with 6 or more than 6 points, then the bases should be located inside of the circular structure
  • #3308 - If the selected group is forming an n-agon with 12 or more than 12 points, the bases should be located inside of the circular structure
  • #3304, #3305 Fixed monomer of cycle on layout should be top left monomer
  • #3496 - Fixing the issue during reading of the molecule data and parse it.
  • #3301 - System provides invalid SDF content (missing semicolon) on mono…
  • #3449 - Bond length become wrong after Arrange as a Ring option applied
  • #3329 - Sequential application of “Create cyclic structure” to different segments of one chain leads to overlapping and distorted topology
  • #3584 - Deadlock in multithread subsearch.
  • #3622 - Fix Bingo-nosql matcher sub tau speed issue
  • #3268 - Cyclic layout issues
  • #3353 - System ignores Implicit H count value in export to SVG/PNG
  • #3303 - Wrong monomer re-layout

Full Changelog: indigo-1.42.0-rc.1...indigo-1.43.0

Indigo-1.42.0

13 May 14:30
f856b9a

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Features

  • #3461 - Export/import multi-tailed arrows to/from CDX/CDXML
  • Enable tau fingerprints in Bingo NoSQL

Bugfixes and improvements

  • #3528 - Bingo NoSQL database format different in Windows and Linux

Full Changelog: indigo-1.41.0-rc.1...indigo-1.42.0

Indigo-1.41.0

13 May 09:55

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Features

  • Run sonarqube only by request

Bugfixes and improvements

  • #3437 - Turn off specific indigo wrappers using cmake
  • #3352 - System should count O and U peptides in Amino Acid natural analog grid
  • #3465 - Substructure match: add parameter to limit tautomer chain search only by matched struct
  • #3446 - Export to CDXML replaces multi-line text labels to many one-line text labels stacked one over another

Full Changelog: indigo-1.40.0-rc.1...indigo-1.41.0

Indigo-1.40.0

23 Feb 15:42
8d9e551

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Features

  • #3375 - Improve the alignment logic

Bugfixes and improvements

  • #3360 - CIP labels aren't added correctly when loading from a cdxml file with no CIP labels
  • #3362 - 13C isotope not recognised in molecular formula when loading from cdxml

Full Changelog: indigo-1.39.0-rc.1...indigo-1.40.0

Indigo-1.39.0

20 Feb 17:41
17e30ee

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Features

  • #3211 - Introducing alignment of sense and antisense chains
  • #3273 - Circular structures improvement - formation of fused rings
  • #3250 - Alignment of sense and antisense strings in AxoLabs format
  • #3337 - Bingo NoSQL tautomer substructure search support.

Bugfixes and improvements

  • #3282 - Can't use indigo as a git submodule
  • #3297 - Random '$$$$V2.0' empty return from conversion to HELM
  • #3306 - Saving to HELM doesn't work for cycled structures consist of nucleosides
  • #3177 - System can't calculate Calculate properties window values for Amino acids with query bonds
  • #3299 - System should set Implicit H value for atoms if the comes without hydrogens from CDXML
  • #3343 - Export to Mol v3000 works wrong for stereo bonds between monomers
  • #3369 - Bingo NoSQL treat empty flags as NONE instead of ALL
  • #3363 - The layout algorithm returns different coordinates on macOS for some tests
  • #3342 - Export ot SVG and PNG doesn't work for stereo bond between monomers, system throws an error: pool: access to unused element
  • #3343 - Export to Mol v3000 works wrong for stereo bonds between monomers
  • #3344 - Export to SVG/PNG works wrong for stereo bonds between monomers

Full Changelog: indigo-1.38.0-rc.1...indigo-1.39.0

Indigo-1.38.0

20 Feb 14:16
c6cc9b1

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Features

  • #3227 - Introducing Copolymer S-group type
  • #3272 - SDF files for library/monomer information
  • #3196 - Support formation of circular structures in flex mode - PoC

Bugfixes and improvements

  • #3239 - System doesn't save monomer expand/collapse state in Mol v3000 for user created monomers (they always come in collapsed state)
  • #3261 - indigoSaveCdxml doesn't support reaction molecules
  • #3269 - System ignored HELM alias for bases on monomer load to Library
  • #3256 - Metals loaded from cdxml are always represented with hydrogens
  • #3237 - Stackoverflow iterate components
  • #3277 - System adds broken Preset to the library (part2)
  • #3278 - System doesn't allow to add monomers with the same structure but different names (part2)
  • #3286 - CHEMBUGS-64 Automapping fails to guard against contradictory reaction center annotation, corrupts future structure export data
  • #3297 - Random '$$$$V2.0' empty return from conversion to HELM
  • #3293 - Library update works wrong if we use empty SDF file
  • #3292 - Save to SDF v2000 works wrong for created monomers
  • #3291 - Layout works wrong
  • #3267 - Export to sugar monomer to AxoLabs error message is wrong
  • #3265 - System should be able to load unknown monomer on any position
  • #3338 - System losts stereo bonds on monomer load to Library
  • #3247 - SVG/PNG: Export of any atom with Isotope (atomic mass) value set doesn't work

Full Changelog: indigo-1.37.0-rc.1...indigo-1.38.0

Indigo-1.37.0

19 Feb 16:38
4a9d3de

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Features

  • #3161 - SDF files for library/monomer information
  • #3152 - AxoLabs format support
  • #3146 - IDT export: use hardcorded nucleotides instead of standard ones

Bugfixes and improvements

  • #2922 - Performing an exact match search results in PostgreSQL termination
  • #3193 - Missing valence of 0 in mol file
  • #3016 - Valence 0 is not taken into account by Molfile export via API
  • #3079 - Export to SVG/PNG doesn't work for molecules with "star" atom. System throws an error: molecule render internal: Query atom type 4 not supported
  • #3141 - One time exception on export to RXN: molecule: casting to molecule is invalid
  • #3178 - Unable to copy user created monomer, exception: Convert error! molecule: casting to molecule is invalid
  • #3070 - Saving to RXN v2000 encloses Polymer labels into double quotes
  • #3206 - Export (or import) to (from) Mol v3000 works wrong for CHEM monomers
  • #3200 - System allows to export not a purely amino acid to Sequence (3-letter code)
  • #3210 - System loads Sequence with numbers in middle
  • #3102 - System can't load sugar-phosphate preset from HELM if sugar provided with HELMAlias name
  • #3220 - System ignores implicitly provided file format on load content thru Paste From Clipboard way
  • #3187 - Export to HELM works wrong for custom monomers imported from HELM with inline SMILES (part 2)
  • #3228 - Loading of AxoLabs with last monomer in brackets doesn't work
  • #3234 - Unable to add user`s peptide, nucleotide and CHEM to the library
  • #3235 - System adds broken Preset to the library
  • #3238 - Monomer name is missed if updated from the API
  • #3212 - Export to RXN disorganize the reaction

Full Changelog: indigo-1.36.0-rc.1...indigo-1.37.0

Indigo-1.36.0

16 Oct 15:01

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Features

  • #905 - Support for pagination in Bingo Elastic
  • #3092 - Avoid overwriting cmake output directories variables
  • #3099 - Support dev container
  • #2893 - Reaction data support in KET-format
  • #3136 - No attachment points check should be performed for terminal CHEMs on IDT import/export
  • #3135 - Mark undefined stereocenters using the standardize function
  • #3085 - HELM annotations support

Bugfixes and improvements

  • #3065 - Indigo build fails when trying to build indigo-depict
  • #3060 - CH labels are recognized as pseudo-atoms when parsing cdxml
  • #3096 - Expand monomer works wrong with selection
  • #3105 - bingo-elastic-python filter broken for exact/substructure
  • #3130 - Bingo-postrgress-fingerprints tests are failing
  • #3071 - Export to RDF V2000 doesn't work if "star" atom on the canvas. System throws exception: Convert error! std::bad_cast
  • #3067 - System can't load HELM with inline SMILES if it has r-site star atom without square brackets
  • #3120 - bingo-elastic-python reaction exact search do not use postprocess actions
  • #3150 - Exception during molecules loading in test fixture
  • #3123 - Unable to paste FASTA content from clipboard
  • #3159 - Export to HELM works wrong for custom monomers imported from HELM with inline SMILES
  • #3068, #3080, #3082, #3086, #3087, #3088, #3090, #3084 - System can't load atom properties (Charge, Isotope and Valence) in SMARTS with "star" atom. System throws exception.
  • #3144, #3147 - Export to IDT baseless preset and modified phosphate
  • #3148 - Export to IDT shouldn't work if monomer at the end has no 3' position IDT code
  • #3169 - Export to IDT doesn't work if R1-only CHEM stays on five prime position

Full Changelog: indigo-1.35.0-rc.1...indigo-1.36.0

Indigo-1.35.0

18 Sep 19:43
195dc64

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Features

  • #2894 - Saving expanded monomers into MOL-files
  • Update monomer expand to follow Indigo structure

Bugfixes and improvements

  • #2900 - CIP labels are always rendered from cdxml
  • #3012 - Create IUPAC Compliant Chemical Formula
  • #3050, #3047, #3048, #3054, #3051 - Loading monomer chain from SDF file works wrong - bonds between monomers got lost/Export RNA monomers from MOLv3000 doesn't work for ACCLDraw export
  • #2928 - Isoelectric Point calculation should take into account occupied leaving groups (exclude them)
  • #3053 - Calculate properties doesn't work for "rich" sequences
  • #3049 - Stereo labels got missied on export to SVG result
  • #3056 - HELM load fails if it contains more than one instance of monomers with aliasHELM property
  • #3045 - Adding substituents to reactants breaks chemical property calculations
  • #3061, #3062 - System can't recognize single rebose or phosphate if loaded from HELM
  • #3069 - Export to RXN doesn't work, system throws exception: Error: memory access out of bounds
  • #3094 - Export of expanded CHEMs works wrong (system losts CHEM type)

Full Changelog: indigo-1.34.0-rc.1...indigo-1.35.0

Indigo-1.34.0

21 Aug 13:04
7a99033

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Features

  • #2899 - Peptide sequence should be auto-deceted at insert
  • #2958 - Map molfile monomers onto library monomers on import
  • #2967 - Support for marking of nucleotide components
  • #2952 - Expand c api to return CIP labels

Bugfixes and improvements

  • #2929 - Isoelectric Point calculation formula seems to be wrong
  • #2964 - System loads base as sugar
  • #2985 - Incorrect Implementation of PKA calculation
  • #2926 - Atom weights in indigo should be updated according to last IUPAC data
  • #2936 - System doesn't calculate melting temperature for mix of nucleotides/nucleosides and unsplit nucleotides/unsplit nucleosides
  • #2965 - System shouldn't allow to export molecules to 3-letter sequence format
  • #2989 - Export (and import) of sequence of nucleosides to HELM works wrong (doesn't work for import)
  • #2993 - System shouldn't consider closing bracket as part of name
  • #2998 - Input fields for ion concentration and oligonucleotides become inactive after entering excessively long number
  • #2970 - Rendering CIP labels breaks the generated svg for firefox
  • #3014 - Wrong bingo-postgres-linux version

Full Changelog: indigo-1.33.0-rc.1...indigo-1.34.0