v0.1.13

What's Changed

• Curate Hashimoto's Thyroiditis entry by @cmungall in #461
• Update Noonan Syndrome by @caufieldjh in #469
• Add comprehensive cystic fibrosis datasets and models research by @github-actions[bot] in #303
• 📄 Regenerate pages, dashboard, and schema docs (2026-03-04) by @github-actions[bot] in #488
• Complete term structure for PAH perturbation in PKU model by @github-actions[bot] in #342
• Add causal model for Semicircular Canal Dehiscence Syndrome by @kevinschaper in #370
• Add Diastrophic Dysplasia curation by @cmungall in #481
• Add Campomelic Dysplasia curation by @cmungall in #482
• Add Cleidocranial Dysplasia curation by @cmungall in #483
• Add Atelosteogenesis Type I curation by @cmungall in #484
• Add Atelosteogenesis Type II curation by @cmungall in #485
• Add Atelosteogenesis Type III curation by @cmungall in #486
• Add Metaphyseal Chondrodysplasia, Schmid Type curation by @cmungall in #490
• Add Metatropic Dysplasia curation by @cmungall in #493
• Add Cough Variant Asthma disorder entry by @balhoff in #487
• 📄 Regenerate pages, dashboard, and schema docs (2026-03-04) by @github-actions[bot] in #498

New Contributors

• @balhoff made their first contribution in #487

Full Changelog: v0.1.12...v0.1.13

v0.1.12

Highlights

Schema docs: https://dismech.monarchinitiative.org/elements/

• by @caufieldjh in #395

What's Changed

• Add otomycosis by @caufieldjh in #358
• Re-add schema and app changes for creation and update date; add date values where missing by @caufieldjh in #375
• Add curated Atopic Dermatitis and Beta Thalassemia disorder entries by @cmungall in #369
• Update Clostridioides difficile Infection by @caufieldjh in #378
• Add taurodontism by @caufieldjh in #382
• Add Chickenpox by @caufieldjh in #373
• Add malaria by @caufieldjh in #381
• Add furunculosis by @caufieldjh in #377
• Add comorbidity infrastructure: COHD scripts, schema slots, and QC by @cmungall in #385
• 📄 Regenerate pages and dashboard (2026-02-21) by @github-actions[bot] in #389
• Add Disease-to-Phenotype (D2P) database comparison tool by @sujaypatil96 in #383
• Add Raynaud Disease entry by @kevinschaper in #348
• Add Netherton Syndrome by @caufieldjh in #380
• Docs update: redesigned schema docs and overview docs by @caufieldjh in #395
• Bulk curation updates for 179 disorder entries by @cmungall in #391
• Add superfences to show rendered Mermaid diagrams in schema docs by @caufieldjh in #431
• Update docs objects by @caufieldjh in #433
• 📄 Regenerate pages, dashboard, and schema docs (2026-02-25) by @github-actions[bot] in #434
• docs: clarify that preferred_term can be more nuanced than the linked ontology term label by @Copilot in #435
• 📄 Regenerate pages, dashboard, and schema docs (2026-02-25) by @github-actions[bot] in #436
• Add Glutaric Aciduria (GA1) disorder entry by @cmungall in #398
• Add internal links between disorder pages and new QC dashboard page by @caufieldjh in #437
• Add Biotinidase Deficiency disorder entry by @cmungall in #406
• Add Carnitine Palmitoyltransferase II Deficiency disorder entry by @cmungall in #408
• Add Primary Carnitine Deficiency disorder entry by @cmungall in #425
• Add Propionic Acidemia disorder entry by @cmungall in #400
• Add 2-Methylbutyryl-CoA Dehydrogenase Deficiency disorder entry by @cmungall in #401
• Add Beta-Ketothiolase Deficiency disorder entry by @cmungall in #405
• Add Citrin Deficiency disorder entry by @cmungall in #410
• Add D-2-Hydroxyglutaric Aciduria disorder entry by @cmungall in #412
• Add Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency disorder entry by @cmungall in #419
• Add Methylmalonic Acidemia disorder entry by @cmungall in #420
• Add Urea Cycle Disorder disorder entry by @cmungall in #427
• Add Ornithine Carbamoyltransferase Deficiency disorder entry by @cmungall in #399
• Add 3-Hydroxy-3-Methylglutaric Aciduria disorder entry by @cmungall in #402
• Add Arginase Deficiency disorder entry by @cmungall in #403
• Add Argininosuccinic Aciduria disorder entry by @cmungall in #404
• Add Carbamoyl Phosphate Synthetase I Deficiency disorder entry by @cmungall in #407
• Add Carnitine-Acylcarnitine Translocase Deficiency disorder entry by @cmungall in #409
• Add Citrullinemia Type I disorder entry by @cmungall in #411
• Add Guanidinoacetate Methyltransferase Deficiency disorder entry by @cmungall in #413
• Add Holocarboxylase Synthetase Deficiency disorder entry by @cmungall in #414
• Add Homocystinuria disorder entry by @cmungall in #415
• Add Isovaleric Acidemia disorder entry by @cmungall in #417
• Add L-2-Hydroxyglutaric Aciduria disorder entry by @cmungall in #418
• Add Mitochondrial Trifunctional Protein Deficiency disorder entry by @cmungall in #421
• Add N-Acetylglutamate Synthase Deficiency disorder entry by @cmungall in #423
• Add Nonketotic Hyperglycinemia disorder entry by @cmungall in #424
• Add Tyrosinemia Type I disorder entry by @cmungall in #426
• Add VLCAD Deficiency disorder entry by @cmungall in #428
• Add Multiple Acyl-CoA Dehydrogenase Deficiency disorder entry by @cmungall in #422
• Add Isobutyryl-CoA Dehydrogenase Deficiency disorder entry by @cmungall in #416
• Add Stargardt Disease knowledge base entry with pathophysiology by @cmungall in #447
• Add Satoyoshi syndrome by @caufieldjh in #396
• Add therapeutic_agent CHEBI/NCIT qualifiers to pharmacotherapy treatments by @sujaypatil96 in #446
• Add Campylobacteriosis by @caufieldjh in #453
• Bump actions/download-artifact from 7.0.0 to 8.0.0 by @dependabot[bot] in #457
• Bump actions/upload-artifact from 6.0.0 to 7.0.0 by @dependabot[bot] in #456
• Add folliculitis by @caufieldjh in #458
• 📄 Regenerate pages, dashboard, and schema docs (2026-03-02) by @github-actions[bot] in #460

Full Changelog: v0.1.11...v0.1.12

v0.1.11

What's Changed

• Add Central Core Myopathy disorder entry by @kevinschaper in #319
• Add Morgagni-Stewart-Morel Syndrome by @AO33 in #284
• Add CADASIL disorder entry by @Vibhorgupta31 in #271
• 📄 Regenerate pages and dashboard (2026-02-14) by @github-actions[bot] in #341
• Add sort by creation or updated date by @caufieldjh in #345
• Curate Hereditary Spherocytosis by @cmungall in #350
• Curate Alpha Thalassemia by @cmungall in #349
• Add Temple-Baraitser syndrome disorder file by @caufieldjh in #344
• Curate Diamond-Blackfan Anemia by @cmungall in #351
• Enhance Fanconi Anemia and CML entries by @cmungall in #352
• 📄 Regenerate pages and dashboard (2026-02-16) by @github-actions[bot] in #355
• Curation: align supports levels across disorder evidence by @cmungall in #357
• Add remaining reference cache, research, src, and test updates by @cmungall in #362
• 📄 Regenerate pages and dashboard (2026-02-16) by @github-actions[bot] in #363
• Add Houge-Janssens Syndrome by @caufieldjh in #347

New Contributors

• @AO33 made their first contribution in #284

Full Changelog: v0.1.10...v0.1.11

v0.1.10

What's Changed

• Fix for Unknown records (from history files) shown in the browser and QC dashboard by @caufieldjh in #301
• Add Kummell disease by @caufieldjh in #270
• Add metadata to downstream causal edges by @cmungall in #290
• 🤖 Weekly Compliance Fix: Add UBERON anatomical locations to IgA Nephropathy (2026-02-11) by @claude[bot] in #300
• 🤖 Weekly Compliance Fix: Add UBERON anatomical locations to Chronic Kidney Disease (2026-02-11) by @claude[bot] in #299
• 🤖 Weekly Compliance Fix: Add UBERON anatomical locations to Glaucoma (2026-02-11) by @claude[bot] in #298
• 🤖 Weekly Compliance Fix: Add UBERON anatomical locations to Liver Cirrhosis (2026-02-11) by @claude[bot] in #297
• 🤖 Weekly Compliance Fix: Add UBERON anatomical locations to GERD (2026-02-11) by @claude[bot] in #296
• Add labyrinthitis by @caufieldjh in #276
• Add Congestive Splenomegaly disorder entry by @kevinschaper in #285
• Bump actions/upload-artifact from 4.6.2 to 6.0.0 by @dependabot[bot] in #225
• Add Joubert syndrome by @caufieldjh in #208
• 📄 Regenerate pages and dashboard (2026-02-12) by @github-actions[bot] in #315
• Remove history pages from rendered HTMLs by @caufieldjh in #318
• 📄 Regenerate pages and dashboard (2026-02-12) by @github-actions[bot] in #317
• create melanoma-DIC comorbidity entry by @katiermullen in #321
• 📄 Regenerate pages and dashboard (2026-02-12) by @github-actions[bot] in #322
• Add 22 skeletal dysplasia entries (Tiers 6-10), completing project by @cmungall in #325
• 📄 Regenerate pages and dashboard (2026-02-13) by @github-actions[bot] in #326
• Add dientamoebiasis by @caufieldjh in #324
• 📄 Regenerate pages and dashboard (2026-02-13) by @github-actions[bot] in #327
• Add banners to indicate resource status by @caufieldjh in #329
• Change UI label from 'Mechanisms' to 'Pathophysiology' by @github-actions[bot] in #335
• Remove case-colliding Holt-Oram page by @kevinschaper in #336
• Clarify evidence_source documents publication evidence type, not curation method by @github-actions[bot] in #334
• Add Empty Nose Syndrome by @caufieldjh in #328
• Add cadmium poisoning by @caufieldjh in #288
• Add CINCA syndrome by @caufieldjh in #279
• Add onboarding documentation for contributors in README and CONTRIBUTING by @github-actions[bot] in #340
• Add arsenic poisoning by @caufieldjh in #293
• Bump actions/download-artifact from 4.3.0 to 7.0.0 by @dependabot[bot] in #226

Full Changelog: v0.1.9...v0.1.10

v0.1.9

Highlight: CF

• CF enhancements by @katiermullen in #291

https://monarch-initiative.github.io/dismech/pages/disorders/Cystic_Fibrosis.html

What's Changed

• Improve causal pathophysiology graphs and add pseudohypoparathyroidism curation by @cmungall in #286
• 📄 Regenerate pages and dashboard (2026-02-10) by @github-actions[bot] in #287
• Add Cogan syndrome by @caufieldjh in #247
• CF enhancements by @katiermullen in #291
• 📄 Regenerate pages and dashboard (2026-02-11) by @github-actions[bot] in #294

New Contributors

• @katiermullen made their first contribution in #291

Full Changelog: v0.1.8...v0.1.9

v0.1.8

highlight: FA entry

92 phenotypes from FA guidelines

One of the most complete phenocams:

What's Changed

• Add Noonan Syndrome with debundled pathophysiology by @cmungall in #245
• Add Laryngotracheoesophageal cleft by @caufieldjh in #237
• Add Danon disease by @sujaypatil96 in #241
• Enhance Wilson Disease entry with expanded pathophysiology and evidence by @cmungall in #251
• Update term caches, add one-up-review skill by @cmungall in #252
• Add 18 skeletal dysplasia disorders by @cmungall in #253
• Add 6 new disorders, update PKD/Tay-Sachs/Tetanus by @cmungall in #254
• Add Ainhum by @caufieldjh in #248
• Reduce Claude review pile-ons by @cmungall in #268
• Expand Inheritance class in schema by @caufieldjh in #269
• Add Salla disease by @caufieldjh in #250
• Add Meckel Syndrome by @caufieldjh in #232
• Add Refeeding Syndrome by @caufieldjh in #224
• Fixes for page rendering KeyError when disorder name is not present by @caufieldjh in #275
• Bump astral-sh/setup-uv from 5 to 7 by @dependabot[bot] in #227
• Add Scimitar syndrome by @caufieldjh in #273
• 📄 Regenerate pages and dashboard (2026-02-08) by @github-actions[bot] in #277
• Update koza dependency to 2.2.0 by @kevinschaper in #280
• Comprehensive Fanconi Anemia enhancements and multi-scheme subtype classification by @cmungall in #278
• 📄 Regenerate pages and dashboard (2026-02-09) by @github-actions[bot] in #281
• Regenerate pages with HPO category grouping by @cmungall in #283

New Contributors

• @sujaypatil96 made their first contribution in #241

Full Changelog: v0.1.7...v0.1.8

v0.1.7

Mechanism comparison browser

What's Changed

• Add Akinetopsia by @caufieldjh in #231
• Enable just fetch reference to take a list of ids by @caufieldjh in #242
• 🤖 Weekly Compliance Fixes (2026-02-03): Bipolar Disorder Cell Types by @claude[bot] in #240
• 🤖 Weekly Compliance Fixes (2026-02-03): Major Depressive Disorder Cell Types by @claude[bot] in #239
• 🤖 Weekly Compliance Fixes (2026-02-03): Generalized Anxiety Disorder Cell Types by @claude[bot] in #238
• Add Gorlin Syndrome (NBCCS) disorder entry by @Vibhorgupta31 in #235
• Replace Brodmann area 19 with secondary visual cortex for V5/MT (issue #233) by @github-actions[bot] in #234
• Add mechanism-level embeddings and cell types space by @cmungall in #244

New Contributors

• @Vibhorgupta31 made their first contribution in #235

Full Changelog: v0.1.6...v0.1.7

v0.1.6

Comorbidity

Adding example comorbities and disease trajectories

Example
https://monarch-initiative.github.io/dismech/pages/comorbidities/com_Atopic_Dermatitis__Type_2_Diabetes_Mellitus.html

What's Changed

• Add KGX edge export via Koza by @kevinschaper in #145
• Add Wissler syndrome by @caufieldjh in #200
• Add projman skill and standardize project file naming by @cmungall in #221
• 📄 Regenerate pages and dashboard (2026-01-31) by @github-actions[bot] in #215
• Add Bird Fancier's Lung by @caufieldjh in #214
• Add Neuromyelitis Optica Spectrum Disorder and neuroimmune project by @cmungall in #143
• classifications and comorbidity by @cmungall in #230
• Bump actions/setup-python from 5.6.0 to 6.2.0 by @dependabot[bot] in #228

Full Changelog: v0.1.5...v0.1.6

v0.1.5

What's Changed

• 🤖 Weekly Compliance Fixes: Triple-Negative Breast Cancer (2026-01-27) by @claude[bot] in #191
• 🤖 Weekly Compliance Fixes: MSI-High Colorectal Cancer (2026-01-27) by @claude[bot] in #192
• 🤖 Weekly Compliance Fixes: MSI-High Endometrial Cancer (2026-01-27) by @claude[bot] in #193
• 🤖 Weekly Compliance Fixes: ER-Positive Breast Cancer (2026-01-27) by @claude[bot] in #194
• 🤖 Weekly Compliance Fixes: Adult T-Cell Leukemia/Lymphoma (2026-01-27) by @claude[bot] in #195
• 📄 Regenerate pages and dashboard (2026-01-27) by @github-actions[bot] in #196
• Add FICUS syndrome by @caufieldjh in #186
• Bump actions/github-script from 6 to 8 by @dependabot[bot] in #4
• Bump pypa/gh-action-pypi-publish from 1.12.4 to 1.13.0 by @dependabot[bot] in #5
• 📄 Regenerate pages and dashboard (2026-01-28) by @github-actions[bot] in #201
• 🤖 Weekly Compliance Fixes (2026-01-28): Von Hippel-Lindau Disease by @claude[bot] in #203
• 🤖 Weekly Compliance Fixes (2026-01-28): Myasthenia Gravis by @claude[bot] in #204
• 🤖 Weekly Compliance Fixes (2026-01-28): Alzheimer's Disease by @claude[bot] in #205
• Add Sengers syndrome by @caufieldjh in #185
• 📄 Regenerate pages and dashboard (2026-01-28) by @github-actions[bot] in #207
• Add gene_term slot to Genetic class for HGNC ontology binding by @github-actions[bot] in #202
• Add Proteus syndrome by @caufieldjh in #199
• 📄 Regenerate pages and dashboard (2026-01-29) by @github-actions[bot] in #209
• Add Silent Sinus Syndrome disorder entry by @justaddcoffee in #206
• Fix pathophysiology bundling by decomposing into atomic mechanisms by @github-actions[bot] in #210
• 📄 Regenerate pages and dashboard (2026-01-30) by @github-actions[bot] in #212

New Contributors

• @justaddcoffee made their first contribution in #206

Full Changelog: v0.1.4...v0.1.5

v0.1.4

UI Changes

https://monarch-initiative.github.io/dismech/app/embeddings/index.html

Diseases can be explored in embedding space

Pathophsyiology embeddings:

Phenotype embeddings:

Treatment embeddings:

What's Changed

• Add evidence and fix ontology terms per PR#33 review by @Copilot in #128
• Add Acne Vulgaris disorder entry by @turbomam in #176
• 🤖 Weekly Compliance Fixes (2026-01-23): Osteoarthritis by @claude[bot] in #179
• 🤖 Weekly Compliance Fixes (2026-01-23): Sickle Cell Disease by @claude[bot] in #178
• 🤖 Weekly Compliance Fixes (2026-01-23): Camptodactyly by @claude[bot] in #177
• feat: add pars planitis disorder curation by @cmungall in #33
• 📄 Regenerate pages and dashboard (2026-01-25) by @github-actions[bot] in #180
• Curation updates, histopathology schema, and embedding browser assets by @cmungall in #183
• Add Peutz Jeghers polyp by @caufieldjh in #165
• Adding cached items by @cmungall in #187
• Expand schema to define evidence source types; update three pages with evidence source types by @caufieldjh in #173
• 📄 Regenerate pages and dashboard (2026-01-27) by @github-actions[bot] in #189

New Contributors

• @turbomam made their first contribution in #176

Full Changelog: v0.1.3...v0.1.4