Skip to content
#

hereditary-cancer

Star

Here are 3 public repositories matching this topic...

Language: All
Filter by language
All 3 HTML 1 Python 1 TeX 1

Bloomed-Health / POLE-Frameshift

Star 2

Research framework for POLE c.138del (p.Leu46Phefs*8); Confirmed germline pathogenic frameshift variant clinically consistent w/ PPAP (reported ultra-hypermutated; tumour signature confirmation pending). Mechanistic models, differential diagnosis, therapeutic strategies, and experimental priorities.

ppap immunotherapy rare-variant pole mutational-signatures tumor-mutational-burden dna-repair precision-oncology cancer-genetics hereditary-cancer loss-of-heterozygosity polymerase-proofreading
  • Updated Jul 1, 2026
  • TeX

faith-ogun / Unravel

Star 0

Five Google ADK / Agent Builder agents watching genomic evidence (ClinVar, gnomAD, AlphaMissense) synced via the Fivetran MCP and, the moment a Variant of Uncertain Significance is reclassified, recompute a calibrated ACMG posterior to draft the patient recontact + family cascade no system sends today. Draft-only, FHIR R4, human-in-the-loop.

bigquery bioinformatics genomics mcp multi-agent healthcare gemini fhir clinical-decision-support firestore acmg variant-interpretation fivetran alphafold hereditary-cancer vertex-ai alphamissense agent-builder google-adk
  • Updated Jun 10, 2026
  • Python

Improve this page

Add a description, image, and links to the hereditary-cancer topic page so that developers can more easily learn about it.

Curate this topic

Add this topic to your repo

To associate your repository with the hereditary-cancer topic, visit your repo's landing page and select "manage topics."

Learn more